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Flashcards in anti-virals Deck (120)
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61

MOA fo raltegravir

inhibits HIV genemoe integration into host cell chrom by reversibly inhibiting HIV integrase

62

a/se of ratelgrivir

increases creatine kinase

63

a/se of increased creatine kinase

raltegrivir, the integrase inhibitor

64

list the fusion inhibitors pelase

enfuvirtide
maroviroc

65

moa of enfuvirtide

a fusion inhibitor
binds gp41 inhibiting viral entry

66

moa of maraviroc

binds CCR5 of t cells and monocytes
inhibits interaction with HIV's gp21

67

a/se of enfurvirtide

skin reaction at injection site

68

ts for chronic hepatitis B

IFNa

69

tx for chronic hepatitis C

IFNa
ribavirin
simeprevir
sofosbuvir

70

tx for Kaposi sarcoma

IFNa

71

tx for hairy cell leukemia

IFNa

72

tx for condyloma acuminatum

IFNa

73

tx for renal cell carcinoma

IFNa

74

tx for malignant melaonma

IFNa

75

tx for multiple sclerosis

IFNb

76

tx for chronic granulomatous disease

IFNg

77

toxos of interferones please

neutropenia
myopathy

78

a/se of neutropenia and myopathy

interferons

79

what are the drugs used for hep C tx?

ribavirin
simeprevir
sofosbuvir

80

moa of ribavirin please

inhibits synth of guanine nucleotides by competitively inhibiting INOSINE MONOPI DEHYDROGENASE

81

what is ribavirin used for

hep C and RSC

82

what is DOC in children for RSV

palivizumba (ribavirin)

83

what is toxicity of ribavirin

hemolytic aneamia
severe teratogen

84

what is the moa of simeprevir

HCV protease inhibitor
prevents viral replication

85

what are uses of simpervir

HCV with ribavirin and pegIFNa

86

what are toxos of simeprevir

rash and photosensitivity

87

anti virals that can give a rash

simeprevir and NNRTis

88

what is the moa of sofosbuvir

inhibits HCV RNA dependent RNA polymerase
chain terminator

89

what is cxl use of sofosbuvir

chronic HSV in combo with ribavirin and or not with peginterdreon

90

what are the toxocs of sofosbuvir

fatigue, headache nausea