ANTIBACTERIALS Reporter 11 Flashcards
(23 cards)
- substances
that inhibit bacterial growth or
kill bacteria
Antibacterials
– substances
that inhibit growth or kill
microorganisms
Antimicrobials
– chemicals
produced by one kind of
microorganism that inhibit the
growth of or kill another
Antibiotics
- “bacteria-killing”
Bactericidal
– inhibits growth of bacteria
Bacteriostatic
also known as prokaryotes (single-celled organisms)
Bacteria
Gram-positive
*Staphylococcus aureus
*Streptococcus pneumoniae
*B Streptococcus
*Clostridium perfringens
Gram-negative
*Neisseria meningitides
*Escherichia coli
*Haemophilus influenzae
Aerobe bacteri
● Mycobacterium tuberculosis
●Psuedomonas aeruginosa
●E. Coli
●Klebsiella P.
●Proteus M.
Anaerobe bacteria
● C. Tetani
● Actinomyces
● Bacteroides
● Prevotella
● Bifidobacterium
the ability of organisms that cause disease to withstand
attack by antimicrobials
Antimicrobial Resistance (AMR
methicillin was developed.
1959
- strains of S. aureus was beginning to become resistant to methicillin.
1968 -
Methicillin is now off the market; treatment of choice for MRSA is
VANCOMYCIN
, is effective against MRSA, VREF, and penicillin-resistant streptococci.
● Linezolid
e RESTRICTED ANTIMICROBIALS:
Cefepime (Fourth-generation
cephalosporin)
2. Ertapenem (Carbapenem)
3. Meropenem (Carbapenem)
4. Vancomycin (Glycopeptide)
5. Amphotericin B (Macrolide) –
antifungal
6. Voriconazole (Triazole) – antifungal
7. Colistin (Polymyxin)
8. Micafungin (Echinocandin) –
antifungal
9. Aztreonam (Carbapenem) –
antifungal
10. Linezolid (Oxazolidinone)
2 Types of Antibacterials:
Narrow-spectrum
Broad-spectrum
Narrow-spectrum - primarily effective against
ONE type of organism.
Broad-spectrum - can be effective against
BOTH gram-positive and gram-negative
organisms.
Therapies:
Empirical
– antibiotic therapy
during the period prior to the
receipt of blood culture and
antibiotic susceptibility test
results = BROAD SPECTRU
Therapies:
Definitive
ve – antibiotic therapy
given after the receipt of test
results (CS).
NARROW SPECTRU
Therapies:
Multi-antibiotic therapy
daily use of several
antibacterials.
SE:
E: GI disturbances (Nursing IVN: meds with meals), ras