Block 56: Lung Flashcards

(46 cards)

1
Q

Bronchiectasis

A

bronchial thickening and dilation to due to a recurrent cycle of bacterial infection, inflammation and tissue damage

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2
Q

In young patient, most common underlying etiology for bronchiectasis is

A

cystic fibrosis

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3
Q

where in the lung is bronchiectasis due to cystic fibrosis located

A

upper lung lobe

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4
Q

common side effect of systemic glucocorticoids seen in labs

A

leukocytosis with neutrophilic predominance

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5
Q

what lab value is expected for hypersensitivity reaction

A

eosinophilia

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6
Q

MOA of ACE

A

metabolism of kinins and substanceP

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7
Q

destruction and permanent damage of the conducting airway occurs in

A

bronchiectasis

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8
Q

pt with COPD and acute-onset shortness of breath, hypoxia and unilaterally decreased breath sounds likely has? most common cause?

A

secondary spontaneous pneumothorax

- alveolar blebs

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9
Q

risk factors for obstructive atelectasis

A
  • foreign body aspiration
  • malignancy
  • severe pneumonia ( mucus plug)
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10
Q

pts develop what after a fat embolsm

A
  • respiratory distress
  • neurological abnormalities
  • petechial rash
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11
Q

acute dyspnea and hypoxia after motor vehicle collision likely has what

A

pulmonary contusion

- he was prone to blunt thoracic trauma

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12
Q

clinical feature of pulmonary contusion

A

intra-alveolar hemorrhage and edema

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13
Q

some clinical features to look for in pulmonary embolism

A
  • pleuritic chest pain
  • tachypnea
  • atrial fibrillation
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14
Q

triad for cardiac tamponade

A
  • distant heart sounds
  • hypotension
  • jugular venous distension
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15
Q

pleuritic chest pain

A

pain when you breathe, cough and sneeze

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16
Q

Peak airway pressure equation

A

Airway resistance + plateau pressure

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17
Q

plateau pressure equation

A

elastic pressure + positive end-expiratory pressure (PEEP)

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18
Q

How is PEEP calculated

A

end-expiratory hold maneuver

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19
Q

lung compliance

A

ability to expand

20
Q

how does pneumonia cause hypoxemia

A

right-to-left intrapulmonary shunting

V/Q mismatch

21
Q

how is theophylline meabolized

A

cytochrome oxidase in liver

22
Q

antibiotic known to decrease theophylline clearance

A

ciprofloxacin

23
Q

patient with acute presentation of dyspnea, chest pain, tachycardia, hypoxia, and clear lung sounds has

24
Q

most common cause of community-acquired pneumonia

A

strept. pneumoniae

25
on the vent, what influences O2? which one are you more likely to reduce to decrease O2
FiO2 (this one) and PEEP
26
on vent what, influences CO2
RR and TV
27
what tumor produced both alpha fetoprotein and human chorionic gonadotropin tumor marker
Nonseminomatous germ cell tumors
28
3 most common causes of chronic cough a
1. postnasal drip 2. asthma 3. GERD
29
MOA of Chlorpheniramine
H1 Antihistamine receptor blocker
30
asthma patient that has sore throat, morning hoarsness, worsening cough only at night, and increased need for her albuteral inhaler following meals also has what
GERD
31
when are antibiotics given in COPD patient
- moderate to severe exacerbation of COPD | - pts needing mechanical ventilation
32
what causes clubbing
magakaryotcytes are not broken down in lungs, and then get stuck in fingers - hypoxia does not cause clubbing
33
what does CT show for pulmonary embolism
wedge-shaped infarction
34
development of clubbing and sudden-onset joint artropathy in chronic smoker suggests? what can cause this
hypertrophic osteoarthropathy | - any lung cancer
35
Name 2 ways you can increase oxygenation on a vent? which one would you increase in ARDS patient and why?
FiO2 and PEEP | - PEEP: prevent alveolar collapse during respiratory cycles and my also reopen some alveoli
36
If high levels (greater than 60%) of FiO2 is required to maintain oxygen, how do you increase the amount of oxygen a patient gets on the vent
PEEP
37
Aspirin-exacerbated respiratory disease is most often seen in patient with a history of
asthma or chronic rhino-sinusitis with nasal polyposis
38
clinical symptoms of aspirin-exacerbated respiratory disease
bronchospasm nasal congestion following aspirin ingeston
39
what type of reaction is aspirin-exacerbated respiratory disease
non-IgE mediated | psuedoallergic drug reaction
40
where are bronchogenic cysts located
middle mediastinum
41
where are thymoma's found
anterior mediastinum
42
where are all neurogenic tumors located in the mediastinum
posterior mediastinum
43
PE for lung consolidation
dullness to percussion increased intensity of breath sounds increased tactile fremitus
44
percent predicted obstructive pattern FEV1/FVC
less than 70%
45
predicted restrictive pattern FEV1/FEV
greater than 70%
46
what organs are involved in granulomatosis with polyangiitis
- upper and lower respiratory tract infection - renal involvement - glomerulonephritis