Cardio- Infections Flashcards
(32 cards)
What is the treatment for Staphylcoccus aureus caused endocarditis when it is methicillin resistant
- Nafcillin
- Oxacillin
Why is clindamycin in the case of ARF relatively reserved from treatment
Can lead to the opportunity for C. Difficile
What is the treatment for Staphylcoccus aureus caused endocarditis when it is with a patient if mild penicillin allergy
Cefazolin
What is the common cause of infective endocarditis due to a skin lesion
Staphylococci
What is the empiric treatment for acute rheumatic fever
-Penicillin G and gentamicin
What is the common cause of infective endocarditis due to an URI
-HÁČEK group
What is the common cause of infective endocarditis due to an oral lesion
-Streptococcal viridans
What is the mechanism of action for daptomycin
Binds to the cell membrane via the calcium-dependent insertion of its lipid tail leading to depolarization, potassium efflux, and rapid cell death
What is the mechanism of action fo colchicine
-Antiinflammatory action mediated by binding to tubulin, preventing polymerization and inhibition of leukocyte migration and phagocytosis
What is the treatment for Staphylcoccus aureus caused endocarditis when it is MRSA
Vancomycin
-Alternate is daptomycin
What is the target for daptomyocin
Gram positive bacteria, similar to MRSA
What is the drug class of gentamycin
Aminoglycosides
What is the treatment for HÁČEK group caused endocarditis
Ceftriaxone
What is the treatment for Staphylcoccus aureus caused endocarditis when it is a brain abcess
Nafcillin
What is used to track treatment in immunocompetent patients
CRP
What is the treatment for enterococcus (mainly faecalis) caused endocarditis
-Gentamicin and penicillin or ampicillin or vancomycin
What is the treatment for pericarditis in immunocompetent patients
NSAIDs and colchicine
What is the empirical treatment for infective endocarditis
IV vancomycin and ceftriaxone
What is the stereotypical lesion found in infective endocarditis
-Vegetation
What are the adverse effects of colchicine
Diarrhea, vomiting, abdominal pain, hairloss, Peripheral neuritis, myopathy
What portions of the heart are commonly affected with acute rheumatic fever (ARF)
Valves, especially the mitral valve
What is the treatment for Staphylcoccus aureus caused endocarditis when it is a severe penicillin allergy
- Vancomycin
- Daptomycin
Which form of cochicine is most commonly shown to have adverse effects
IV over oral
What is the process of desensitization
Small dose of penicillin is given every 15-30 minutes following no reaction until 2 million units is reached
