GI- IBD Drugs

Question 1

What drug class is Olsalazine

Answer 1

5-ASA

Question 2

What are the classes of drugs that can be given for UC

Answer 2

-5-ASA
JAK inhibator
TNF inhibator
Alpha 4 inhibator

Question 3

What drug class is Balsalazide

Answer 3

5-ASA

Question 4

What is the structure of balsalzide

Answer 4

Inert carrier and 5-ASA

Question 5

What drug class is sulfsalazine

Answer 5

5-ASA

Question 6

What is the structure of Sulfasalazine

Answer 6

5-ASA with sulfapyridine

Question 7

What is the route of administration for Ustekinumab for maintenance

Answer 7

SubQ

Question 8

What is the route of administration for Ustekinumab for induction

Answer 8

IV single infusion

Question 9

What drug class is Golimumab

Answer 9

TNF inhibator

Question 10

What is infliximab used to treat and how is it administered

Answer 10

Moderate to severe UC and CD

-IV every 8 weeks

Question 11

What is Tofacitinib used to treat and how is it administered

Answer 11

Moderate to severe UC

Question 12

What is the structure of Olsalazine

Answer 12

2 molecules of 5-ASA

Question 13

What are the drugs that can be given for Crohn disease

Answer 13

IL12/23 inhibators
TNF alpha inhibitors
Alpha-4 inhibators

Question 14

Alpha 4 integrin inhibators have which severe complication associated

Answer 14

Progressive multifocal leukoencephalopathy

Question 15

What drug class is Tofacitinib

Answer 15

JAK inhibators

Question 16

What is the structure of Mesalamine

Answer 16

Single 5-ASA

Question 17

What drug class is Mesalamine

Answer 17

5-ASA

Question 18

What drug class is alpha4 integrin inhibator

Answer 18

Vedolizumab

Question 19

What is the drug Balsalazide used to treat

Answer 19

Only for active UC in males

Question 20

Which TNF inhibitor is different than the others with regard to structure

Answer 20

All are IgG antibodies except certolizumab, which is a Fab

Question 21

What drug class is natalizumab

Answer 21

Alpha 4 integrin inhibator

Question 22

What drug class is Inflizimab

Answer 22

TNF inhibator

Question 23

What drug class is ustekinumab

Answer 23

IL12/23 inhibator

Question 24

What is golimumab used to treat and how is it administered

Answer 24

Moderate to severe UC only

-SubQ every 4 weeks

Question 25

What drug class is infliximab

Answer 25

TNF inhibitor

Question 26

What is the certolizumab used to treat and how is it administered

Answer 26

Moderate to severe CD only | SuqQ every 4

Question 27

What are 5-ASA agents used to treat, and which are the exceptions

Answer 27

Mild to moderate UC - Olsalazine - Balsalazide

Question 28

What is Natalizumab used to treat and how is it administered

Answer 28

Moderate to sever CD | -IV every 4 weeks

Question 29

What is adalimumab used to treat and how is it administered

Answer 29

Moderate to severe UC and CD | SubQ every 2 weeks

Question 30

What is vedolizumab used to treat and how is it administered

Answer 30

Moderate to severe CD or UC | -IV every 8 weeks

Question 31

What is the drug Olsalazine used to treat

Answer 31

Maintenance of UC

Question 32

What drug class is certolizumab

Answer 32

TNF inhibator

Question 33

What is IL-12/23 inhibitors used to treat

Answer 33

Moderate to severe CD

Question 34

What drug class is TNF- inhibators

Answer 34

Adalimumab