Gi-Nausea And Vomiting Flashcards Preview

Pharmacology & Drugs > Gi-Nausea And Vomiting > Flashcards

Flashcards in Gi-Nausea And Vomiting Deck (55):
1

What adverse effects are common with histamine antagonists

Central anticholinergic properties

2

What are the drugs for vertigo

Meclizine or
Cyclizine

3

What are the drugs used to treat diabetic gastroparesis

Metroclopramide

4

What class of antiemetic agents are 5HT antagonists

Strong

5

What drug class is Dimenhydrinate

Histamine antagonist

6

What class of drug is Nabilone

Class 2 cannabinoid

7

What are some side effects of domamine antagonists

Anticholinergic side effects

8

What drug class is aprepitant

Neurokinin Antagonist

9

What drug class is dronabinol

Cannabinoid

10

What are the general pharmakenetics of 5HT antagonists and what are the exceptions

Short half life, except for:
-Palonosetron
-Granisetron

11

What is alosetron used to treat

IBS-D

12

What drug class is Diphenhydramine

Histamine antagonist

13

What drug class is perphanazine

Dopamine antagonist

14

What is the drug combination for medium emetogenic regimin

5HT antagonist
Corticosteroid

15

What drug class is Palonosetron

5 HT antagonist

16

What is the combination therapy for high emtogenic regimen

-Neurokinin receptor antagonist
-5HT antagonist
-Corticosteroid

17

What is the level of antimumetics are cannabinoid

Strong

18

What drug class is metoclorpradine

Dopamine antagonist (only one not a phenothiazine)

19

What are the complications of serotonin antagonists

Serotonin syndrome
-Prolonged QT
-Torsade’s

20

What level of anti-emetics are dopamine antagonists

Weak to moderate

21

What is the mechanism of action of the neurokinin antagonists

Blockage of receptors in the CTZ/VC

22

What is the treatment as a prophylaxis of post operative N/V (PONV)

Aprepitant (3 Hours before administration of anesthesia)

23

What are the therapy uses for neurokinin antagonists

Chemotherapy induced N/V (CINV)

24

What are the side effects of scopolamine

Significant anticholinergic properties

25

What drug class is cyclizine

Histamine antagonist

26

What drug class is granisetron

5HT antagonist

27

What level of Anti-emetic agent is Neurokinin antagonists

Moderate

28

What is the use for cyclizine

Motion sickness/vertigo only

29

What drug class is Fosnetupitant

Neurokinin antagonists

30

What drug class is scopolamine

M1 antagonist

31

What level of Anti-emetic are histamine antagonists

Weak

32

What are the drugs for motion sickness

-Scopolamine
-Dimenhydrinate
-Meclizine

33

What drug class is nabilone

Cannabinoid agonist

34

What class of drug is dronabinol

Class 3 cannabinoid

35

What drug class is hydroxyzine

Histamine antagonist

36

What drug class is netupitant

Neurokinin antagonist

37

What is usually the effective combination therapy with neurokinin antagonists

Glucocorticoidsteroid

38

What drug class is meclizine

Histamine antagonist

39

What is the low emetogenic regimen

-Corticosteroid or
-5HT antagonists or
-Metoclopramie or
-prochloroperazine

40

What drug class is promethazine

Histamine antagonist

41

What drug class is Fosaprepitant

Neurokinin antagonist

42

What drug class is chloropromazine

Dopamine antagonist

43

What is the use for meclizine

Motion sickness/vertigo only

44

What drug class is phenothiazine’s

Dopamine antagonist

45

Which of 5HT antagonists has the highest risks

Dolasetron

46

What is scopolamine used to treat

Motion sickness (path worn for 72 hours)

47

Which interactions must be monitored with cannabinoids

CNS depressants
CV drugs
Sympathomimetics

48

What drug class is dolasetron

5HT receptor antagonist

49

What histamine antagonists are for motion sickness/vertigo

Meclizine
Cyclizine

50

What are the therapeutic uses

Chemotherapy N/V (CINV)
Radiation induced N/V (RINV)
Post operative N/V (PONV)
NV or Pregnacny (NVP)

51

What drug class is Ondansetron

5HT antagonist

52

What drug class is prochloroperazine

Dopamine antagonist

53

What is a side effect of metoclopramide, but can also be used as a treatment

Stimulate the ACh action in the GI, leading to increased motility in the GI

54

Which histamine receptor antagonist is given to pregnant patients

Doxylamine with pyridoxine (B6)

55

What drug class is rolapitant

Neurokinin Antagonist