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Pharmacology & Drugs > Gi-Nausea And Vomiting > Flashcards

Gi-Nausea And Vomiting Flashcards

(55 cards)

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1
Q

What adverse effects are common with histamine antagonists

A

Central anticholinergic properties

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2
Q

What are the drugs for vertigo

A

Meclizine or

Cyclizine

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3
Q

What are the drugs used to treat diabetic gastroparesis

A

Metroclopramide

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4
Q

What class of antiemetic agents are 5HT antagonists

A

Strong

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5
Q

What drug class is Dimenhydrinate

A

Histamine antagonist

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6
Q

What class of drug is Nabilone

A

Class 2 cannabinoid

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7
Q

What are some side effects of domamine antagonists

A

Anticholinergic side effects

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8
Q

What drug class is aprepitant

A

Neurokinin Antagonist

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9
Q

What drug class is dronabinol

A

Cannabinoid

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10
Q

What are the general pharmakenetics of 5HT antagonists and what are the exceptions

A

Short half life, except for:

  • Palonosetron
  • Granisetron
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11
Q

What is alosetron used to treat

A

IBS-D

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12
Q

What drug class is Diphenhydramine

A

Histamine antagonist

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13
Q

What drug class is perphanazine

A

Dopamine antagonist

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14
Q

What is the drug combination for medium emetogenic regimin

A

5HT antagonist

Corticosteroid

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15
Q

What drug class is Palonosetron

A

5 HT antagonist

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16
Q

What is the combination therapy for high emtogenic regimen

A
  • Neurokinin receptor antagonist
  • 5HT antagonist
  • Corticosteroid
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17
Q

What is the level of antimumetics are cannabinoid

A

Strong

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18
Q

What drug class is metoclorpradine

A

Dopamine antagonist (only one not a phenothiazine)

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19
Q

What are the complications of serotonin antagonists

A

Serotonin syndrome

  • Prolonged QT
  • Torsade’s
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20
Q

What level of anti-emetics are dopamine antagonists

A

Weak to moderate

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21
Q

What is the mechanism of action of the neurokinin antagonists

A

Blockage of receptors in the CTZ/VC

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22
Q

What is the treatment as a prophylaxis of post operative N/V (PONV)

A

Aprepitant (3 Hours before administration of anesthesia)

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23
Q

What are the therapy uses for neurokinin antagonists

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A

Chemotherapy induced N/V (CINV)

24
Q

What are the side effects of scopolamine

Study These Flashcards
A

Significant anticholinergic properties

25
What drug class is cyclizine
Histamine antagonist
26
What drug class is granisetron
5HT antagonist
27
What level of Anti-emetic agent is Neurokinin antagonists
Moderate
28
What is the use for cyclizine
Motion sickness/vertigo only
29
What drug class is Fosnetupitant
Neurokinin antagonists
30
What drug class is scopolamine
M1 antagonist
31
What level of Anti-emetic are histamine antagonists
Weak
32
What are the drugs for motion sickness
- Scopolamine - Dimenhydrinate - Meclizine
33
What drug class is nabilone
Cannabinoid agonist
34
What class of drug is dronabinol
Class 3 cannabinoid
35
What drug class is hydroxyzine
Histamine antagonist
36
What drug class is netupitant
Neurokinin antagonist
37
What is usually the effective combination therapy with neurokinin antagonists
Glucocorticoidsteroid
38
What drug class is meclizine
Histamine antagonist
39
What is the low emetogenic regimen
- Corticosteroid or - 5HT antagonists or - Metoclopramie or - prochloroperazine
40
What drug class is promethazine
Histamine antagonist
41
What drug class is Fosaprepitant
Neurokinin antagonist
42
What drug class is chloropromazine
Dopamine antagonist
43
What is the use for meclizine
Motion sickness/vertigo only
44
What drug class is phenothiazine’s
Dopamine antagonist
45
Which of 5HT antagonists has the highest risks
Dolasetron
46
What is scopolamine used to treat
Motion sickness (path worn for 72 hours)
47
Which interactions must be monitored with cannabinoids
CNS depressants CV drugs Sympathomimetics
48
What drug class is dolasetron
5HT receptor antagonist
49
What histamine antagonists are for motion sickness/vertigo
Meclizine | Cyclizine
50
What are the therapeutic uses
Chemotherapy N/V (CINV) Radiation induced N/V (RINV) Post operative N/V (PONV) NV or Pregnacny (NVP)
51
What drug class is Ondansetron
5HT antagonist
52
What drug class is prochloroperazine
Dopamine antagonist
53
What is a side effect of metoclopramide, but can also be used as a treatment
Stimulate the ACh action in the GI, leading to increased motility in the GI
54
Which histamine receptor antagonist is given to pregnant patients
Doxylamine with pyridoxine (B6)
55
What drug class is rolapitant
Neurokinin Antagonist

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