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Neuro-Movment Disorder Drugs Flashcards

(47 cards)

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1
Q

Which dopamine receptor is targeted for Pramipexole

A

D3

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2
Q

What class of drug is tolcapone

A

Catechol-O-methyltransferase

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3
Q

What is the origin/nature of amandtadine

A

Antiviral agent

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4
Q

What is zinc sulfate used to treat

A

Wilson disease

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5
Q

What is potassium disulfide used to treat

A

Wilson disease

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6
Q

What class of drug is benztropine

A

Anticholinergic

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7
Q

What class of drug is biperiden

A

Anticholinergic

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8
Q

What class of drug is procyclidine

A

Anticholinergic

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9
Q

What is the mechanism of action for Penicillamine

A

Cheating agent that forms a stable complex with copper and excreted via kidney

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10
Q

During administration of domaine receptor agonists, what side effects are seen in movement changes

A

Choreoathetosis (intermediate speed) of the face and distal extremities

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11
Q

MAO-B is responsible for metabolizing which compounds

A

Phenylethylamine and benzylamine

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12
Q

Where does apomorphine act

A

Dopamine (D2) receptors

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13
Q

What class of drug is entacapone

A

Catechol-O-methyltransferase inhibitor

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14
Q

Antiphycotic drugs can cause which side effects

A

Extrapyramidal syndromes, weight gain, sedation, irritability, and phobias

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15
Q

Which two beta blocking drugs can be given to someone with beta-1 tremors

A
  • Metoprolol

- Propranolol

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16
Q

What are 2 drugs that can be used to treat Huntington disease

A
  • reserpine

- tetrabenazine

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17
Q

Which patient sets is administration of dopamine agonists contraindicated

A
  • psychotic illness
  • MI
  • peptic ulceration
  • peripheral vascular disease
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18
Q

MAO-A is primarily responsible for the metabolism of which compound

A

NE and serotonin

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19
Q

What class of drug is apomorphine

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A

Dopamine agonist

20
Q

During administration of domaine receptor agonists, what side effects are seen in the GI

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A

Anorexia, nausea, vomiting, constipation

21
Q

What class of drug is selegiline

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A

MOA inhibitor

22
Q

What is the mechanism of action for trientine, zinc acetate, and zinc sulfate

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A

Chetalating agent which increases the fecal excretion of copper by decreased GI absorption

23
Q

What are treatments for restless leg syndrome

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A
  • Resolving iron deficiency

- dopamine agonists

24
Q

What class of drug is pramipexole

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A

Dopamine agonist

25
What is penicillamine used to treat
Wilson disease
26
What class of drug is ropinirole
Dopamine agonist
27
What class of drug is rasagiline
MOA inhibitor
28
Which serotonin receptor can be used for tremors
Topirimate
29
What class of drug is trihexyphenidyl
Anticholinergic
30
Which dopamine receptor is targeted for Bromocriptine
D2
31
Which dopamine receptor is targeted for ropinirole
D2
32
Clonidine and guanfacine can be used to alternatively treat which condition
Tics
33
What is Trientine used to treat
Wilson’s disease
34
What is the only drug that is known to increase the survival of ALS
Riluzole
35
What part of the body does entacapone affect
Peripheral only
36
What is the mechanism of action for potassium disulfide
Reduced intestinal absorption of copper
37
What is zinc acetate used to treat
Wilson disease
38
What condition can pimozide used to treat
Tics
39
What is the mechanism of action of reserpine and tetrabenzazine
Impairs dopamine transmission
40
What is the mechanism of action for Riluzole
Inhibits glutamate release and activation of sodium channels
41
What part of the body does tolcapone act in
Central and peripheral acting
42
During administration of domaine receptor agonists, what side effects are seen in the CV
Postural hypotension, digital spasms,peripheral edema and arrhythmias
43
What is the method that Selegiline works
Inhibits MAO-B, slowing the breakdown of dopamine
44
What is the method that Rasagiline works
Inhibition of MAO-B and works as a neuroprotective agent
45
What class of drug is orphenadrine
Anticholinergic
46
Which benzodiazepine can be used for tremors
Alprazolam
47
What class of drug is bromocriptine
Dopamine agonist

Pharmacology & Drugs (43 decks)

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