Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Pharmacology & Drugs > Respiratory Drugs- HIV > Flashcards

Respiratory Drugs- HIV Flashcards

(70 cards)

Start Studying
1
Q

Enfuvirtide

A

Fusion inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Fosamprenavir

A

Protease inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Tipranavir

A

Protease inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Metabolism of etravirine

A

Inducer of 3A4

Inhibitor of 2C9 and 2C19

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Adverse effects of Zidovudine

A

Blood issues as macrocytic anemia and neutropenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Adverse effects of efavirenz

A

CNS issues such as drowsiness and dizziness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Darunavir

A

Protease inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Adverse effects of darunavir

A

Sulfa allergies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is required with elvitegravir

A

Booster with cobicistat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Zanamivir

A

Anti-influenza

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Nevirapine

A

non-NRTI in pregnant mothers and to the neonate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What must darunavir be coadministered with

A

Ritonavir or cobicistat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Protease inhibitor for pregnant women

A

Atazanavir

Darunavir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

MOA of entry inhibitors

A

Binds to CCR5 to prevent the entry

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Metabolism of elvitegravir

A

CYP3A4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Delaviridine

A

non-NRTI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

When is lopinavir used

A

Combinationn with ritonavir as a booster

-In pregnant women

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Peramivir

A

Anti-influenza

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Benfits of enfuvirtide

A

None drug drug interactions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Efavirenz

A

non-NRTI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Adverse effects of Fosamprenavir

A

Sulfa allergies

headache, neausea, diarrhea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Oseltamivir

A

Anti-influenza

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Fosamprenavir

A

Protease inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

MOA or protease inhibitors

A

Blocks protease that allows mature vision

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Etravirine
Diarylpyrimidine non-NRTI
26
Didanosine
Deoxyadenoxine NRTIs
27
Adverse effects and resistant mechanism of al NRTIs
Mito toxicity | Point mutations in RT
28
MOA for Peranivir
Inhibits neuromenidase
29
What are the boosting agents and how do they work
Ritonavir • Cobicistat Affect CYP3A4
30
Maraviroc
Entry inhibitors
31
When is dolutegravir used
Treatment of naive pts with: 1- tenofovir/emtricitabine or 2-abacavir/lamivudine
32
Metabosism of protease inhibitors
CYP3A4
33
Metabolism of Efavirenz
CYP3A4 and 2B6
34
Metabolism of delavirdine
CYP3A4 and 2D6
35
Atazanavir
Protease inhibitor
36
Nelfinavir
Protease inhibitor
37
What is commonly used as a booster with Saqyunavir
Ritonavir to reduce toxicities
38
MOA of non-NRTI
Binds directly to RT resulting in allosteric inhibiton
39
MOA of integrase strand transfer inhibitor
Prevents integration into the host DNA
40
Ritonavir
Protease inhibitor
41
MOA for oseltamivir
Inhibits neuormenidase
42
Stavudine
Thymidine NRTIs
43
Zidovudine
Deoxythymidine NRTIs
44
Adverse affects of delavirdine
Skin rash and pregnancy effects
45
Adverse effects of protease inhibitors
GI intolerance | -lipid changes such as hyperglycemia, hyperlipidemia, fat redistribution, cushing like symptoms
46
What other condition is treated with emtricitabine and lamivudine
HBV
47
Rilpivirine
Diarylpyrimidine non-NRTI in pregnanct women
48
Lopinavir
Protease inhibitor
49
Adverse effects of Nelfinavir
Gas
50
MOA for Zanamivir
Inhibits neuromenidase
51
Indinavir
Protease inhibitor
52
Adverse effects of tiranavir
Sulfa allergy Maculopapular rash D/N/V
53
Adverse effects of stavudine
Sensory neuropathy especially in immunosuppression pt
54
Emtricitabine
Fluoridated version of lamivudine NRTIs
55
Dolutegravir
Integrase strand transfer inhibitor
56
Adverse effects of Indinavir
Unconjugated hyperbilirubinemia and nephrolithisasis (must drung water to prevent)
57
What mutation would grant resistance against maraviroc
V3 loop of gp120
58
Abacavir
Guanosine NRTIs
59
Adverse effects of emtricitabine
Hyperpigmentation if palms and soles
60
MOA of fusion inhibitors
Binds to gp41 and prevents binding and fusion with cell membrane
61
Saquinavir
Protease inhibitor
62
When is ritonavir used
As a booster due to its inhibition of 3A4 and GI issues
63
Tenofovir
Acyclic adenosine NRTIs
64
Lamivudine
Cytosine NRTIs
65
When is raltegravir recommended
Naive persions with HAART and Pregnancy
66
Elvitegravir
Integratse strand transfer inhibitor
67
Pharmokinetics and adverse effects of enfuvirtide
SubQ bid, reactions at injection site
68
Raltegravir
Integrase strand transfer inhibitor
69
When is Tiranavir
When resistance to other Protease inhibitors
70
Adverse effects of didanosine
Pancreatitis (especially with alcohol abuse, hyperTAGs) | Retinal changes and optic neuritis

Pharmacology & Drugs (43 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions