Respiratory Drugs- COPD and asthma

Question 1

Mometasone

Answer 1

Inhaled corticosteroids

Question 2

interactions with fluticasone

Answer 2

Strong inhibitor of 3A4

May increase chances of systemic corticosteroid effects

Question 3

Albuterol

Answer 3

Short Acting Beta Agonist

Question 4

Uses for triamcinolone

Answer 4

Prophylactic for asthma, can also be used to weene off systemic corticosteroids

Question 5

Zafirlukast

Answer 5

Leukotriene inhibitor

Question 6

Salmeterol

Answer 6

Long Acting Beta Agonist

Question 7

Tiotropium

Answer 7

Anticholinergic

Question 8

Use of budesonide

Answer 8

Maintenice of asthma in >6

Question 9

MOA of Zafirlukast

Answer 9

Antagonist of D4 and E4, components of slow reacting anaphylaxis

Question 10

What are the drug drug interactions of Zileuton

Answer 10

Increases theophylline levels, warfarin levels, propranolol levels and beta blocker activity

Question 11

Uses for pirbuterol

Answer 11

Prevention and reversal of bronhcospasms in patients >12

Question 12

Acilinium

Answer 12

Anticholinergic

Question 13

When is terbutaline used

Answer 13

Prophylaxis for ages >12

Question 14

Uses of olodaterol

Answer 14

Once daily for COPD

Question 15

Uses for fluticasone

Answer 15

Prophylactic for younger than 4 years old

Question 16

Uses for metaproterenolol

Answer 16

Bronchodilation for asthma or COPD

Question 17

Use of Zafirlukast

Answer 17

Prophylaxis and chronic treatment of asthma in adults and children >5

Question 18

Beclomethasone

Answer 18

Inhaled corticosteroids

Question 19

What is the method of administration for terbutaline

Answer 19

IV

Question 20

Metabolism of salmeterol

Answer 20

3A4

Question 21

What is the adverse effect with beclomethasone

Answer 21

Care when transferring from systemic corticosteroids due to death from adrenal insufficiency. It takes time for the axis to recover

Question 22

Ipratropium

Answer 22

Anticholinergic

Question 23

Uses of indacaterol

Answer 23

COPD`

Question 24

What are the adverse effects of Zafirlukast

Answer 24

Hepatotoxicity

Question 25

Pirbuterol

Answer 25

Beta agonist

Question 26

MOA for Monelukast

Answer 26

Selectively binds to CysLT1 receptor, inhibiting D4 without any agonist activity.

Question 27

Olodaterol

Answer 27

Long Acting Beta Agonist

Question 28

Ciclesonide

Answer 28

Inhaled corticosteroids

Question 29

Adverse effects of Fomoterol

Answer 29

Asthma related deaths and hospitalizations if not already on a long term controller of asthma

Question 30

What is a risk for all long Acting Beta Agonist

Answer 30

Increased risk for asthma related deaths and hospitalizations

Question 31

Use for Monelukast

Answer 31

Allergies and prevention of asthma attacks

Question 32

Cautions of budesonide

Answer 32

Milk allergies or where primary treatment of status asthmaticus or acute episodes where intenstive measures are needed

Question 33

Fluticasone

Answer 33

Inhaled corticosteroid

Question 34

Use of salmeterol

Answer 34

Asthma in pts >4, exercise induced asthma, maintenence of COPD

Question 35

Adverse effects of metaproterenolol

Answer 35

CV negative effects

Question 36

Theophylline

Answer 36

Methylxanthines

Question 37

Fomoterol

Answer 37

Long Acting Beta Agonist

Question 38

Indacaterol

Answer 38

Long Acting Beta Agonist

Question 39

Uses for mometasone

Answer 39

Asthma prophylactic in patients >4

Question 40

Triamcinolone

Answer 40

Inhaled corticosteroid

Question 41

Metabolism of budesonide

Answer 41

CYP3A4

Question 42

Budesonide

Answer 42

Inhaled corticosteroids

Question 43

MOA of Zileuton

Answer 43

Inhibitor of 5-lipoxygenase, so all of B4,C4,D4,E4

Question 44

Use for levalbuterol

Answer 44

Prevention or treatment of bronhcospasms in pt >4

Question 45

Flunosolide

Answer 45

Inhaled corticosteroids

Question 46

Omalizumab

Answer 46

Monoclonal antibody to IgE

Question 47

Use for fomoterol

Answer 47

Treatment of asthma >5 yrs old, as an add on to long term corticosteroids, prevention of excersice induced asthma, treatment of COPD

Question 48

What is the drug interactionwith zafirlukast

Answer 48

Coadministration with Warfarin will increase the prothrombin time

Question 49

Montelukast

Answer 49

Leukotriene antagonist

Question 50

Uses for Omalizumab

Answer 50

Severe asthma in pts older than 6, chonic idiopathic urticaria

Question 51

3 methods of bronchodilation

Answer 51

- B2 agonsts - Anticholinergic - Methlyxanthines

Question 52

Adverse effects of salmeterol

Answer 52

Severe allergies to milk | Patients must be on concurrent use of inhaled corticosteroid

Question 53

Terbutaline

Answer 53

Beta Agonist

Question 54

Levalbuterol

Answer 54

Beta agonist

Question 55

Zileuton

Answer 55

Leukotriene antagonist

Question 56

What conditions are contraindicated for theophylline

Answer 56

Active Peptic ulcer disease seizure diseases cardiac arrhythmias

Question 57

What are the adverse effects of tiotropium

Answer 57

- Not for acute use or rescue medication | - Immediate hypersentitivity risk, especialy with milk protieins

Question 58

Use for ciclesonide

Answer 58

Prophalayxis for >12 yrs old

Question 59

Effects of methylxanthines

Answer 59

Broncho dilation | suppression of the airway responses

Question 60

Uses for flunosolide

Answer 60

Maintenance of asthma in >6 years old, and in those trying to weene off of oral corticosteroids

Question 61

Adverse effects of Zileuton

Answer 61

Pharynolaryngeal pain, elevation of hepatic enzymes

Question 62

Metaoroterenol

Answer 62

Beta agonist