Respiratory Drugs- COPD and asthma Flashcards Preview

Pharmacology & Drugs > Respiratory Drugs- COPD and asthma > Flashcards

Flashcards in Respiratory Drugs- COPD and asthma Deck (62):
1

Mometasone

Inhaled corticosteroids

2

interactions with fluticasone

Strong inhibitor of 3A4
May increase chances of systemic corticosteroid effects

3

Albuterol

Short Acting Beta Agonist

4

Uses for triamcinolone

Prophylactic for asthma, can also be used to weene off systemic corticosteroids

5

Zafirlukast

Leukotriene inhibitor

6

Salmeterol

Long Acting Beta Agonist

7

Tiotropium

Anticholinergic

8

Use of budesonide

Maintenice of asthma in >6

9

MOA of Zafirlukast

Antagonist of D4 and E4, components of slow reacting anaphylaxis

10

What are the drug drug interactions of Zileuton

Increases theophylline levels, warfarin levels, propranolol levels and beta blocker activity

11

Uses for pirbuterol

Prevention and reversal of bronhcospasms in patients >12

12

Acilinium

Anticholinergic

13

When is terbutaline used

Prophylaxis for ages >12

14

Uses of olodaterol

Once daily for COPD

15

Uses for fluticasone

Prophylactic for younger than 4 years old

16

Uses for metaproterenolol

Bronchodilation for asthma or COPD

17

Use of Zafirlukast

Prophylaxis and chronic treatment of asthma in adults and children >5

18

Beclomethasone

Inhaled corticosteroids

19

What is the method of administration for terbutaline

IV

20

Metabolism of salmeterol

3A4

21

What is the adverse effect with beclomethasone

Care when transferring from systemic corticosteroids due to death from adrenal insufficiency. It takes time for the axis to recover

22

Ipratropium

Anticholinergic

23

Uses of indacaterol

COPD`

24

What are the adverse effects of Zafirlukast

Hepatotoxicity

25

Pirbuterol

Beta agonist

26

MOA for Monelukast

Selectively binds to CysLT1 receptor, inhibiting D4 without any agonist activity.

27

Olodaterol

Long Acting Beta Agonist

28

Ciclesonide

Inhaled corticosteroids

29

Adverse effects of Fomoterol

Asthma related deaths and hospitalizations if not already on a long term controller of asthma

30

What is a risk for all long Acting Beta Agonist

Increased risk for asthma related deaths and hospitalizations

31

Use for Monelukast

Allergies and prevention of asthma attacks

32

Cautions of budesonide

Milk allergies or where primary treatment of status asthmaticus or acute episodes where intenstive measures are needed

33

Fluticasone

Inhaled corticosteroid

34

Use of salmeterol

Asthma in pts >4, exercise induced asthma, maintenence of COPD

35

Adverse effects of metaproterenolol

CV negative effects

36

Theophylline

Methylxanthines

37

Fomoterol

Long Acting Beta Agonist

38

Indacaterol

Long Acting Beta Agonist

39

Uses for mometasone

Asthma prophylactic in patients >4

40

Triamcinolone

Inhaled corticosteroid

41

Metabolism of budesonide

CYP3A4

42

Budesonide

Inhaled corticosteroids

43

MOA of Zileuton

Inhibitor of 5-lipoxygenase, so all of B4,C4,D4,E4

44

Use for levalbuterol

Prevention or treatment of bronhcospasms in pt >4

45

Flunosolide

Inhaled corticosteroids

46

Omalizumab

Monoclonal antibody to IgE

47

Use for fomoterol

Treatment of asthma >5 yrs old, as an add on to long term corticosteroids, prevention of excersice induced asthma, treatment of COPD

48

What is the drug interactionwith zafirlukast

Coadministration with Warfarin will increase the prothrombin time

49

Montelukast

Leukotriene antagonist

50

Uses for Omalizumab

Severe asthma in pts older than 6, chonic idiopathic urticaria

51

3 methods of bronchodilation

-B2 agonsts
-Anticholinergic
-Methlyxanthines

52

Adverse effects of salmeterol

Severe allergies to milk
Patients must be on concurrent use of inhaled corticosteroid

53

Terbutaline

Beta Agonist

54

Levalbuterol

Beta agonist

55

Zileuton

Leukotriene antagonist

56

What conditions are contraindicated for theophylline

Active Peptic ulcer disease
seizure diseases
cardiac arrhythmias

57

What are the adverse effects of tiotropium

-Not for acute use or rescue medication
-Immediate hypersentitivity risk, especialy with milk protieins

58

Use for ciclesonide

Prophalayxis for >12 yrs old

59

Effects of methylxanthines

Broncho dilation
suppression of the airway responses

60

Uses for flunosolide

Maintenance of asthma in >6 years old, and in those trying to weene off of oral corticosteroids

61

Adverse effects of Zileuton

Pharynolaryngeal pain, elevation of hepatic enzymes

62

Metaoroterenol

Beta agonist