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Pharmacology & Drugs > GI-Diarrhea And Abdominal Pain > Flashcards

GI-Diarrhea And Abdominal Pain Flashcards

(45 cards)

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1
Q

What drug class is diphenoxylate

A

Opioid agonists

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2
Q

What is a severe side effect of alosetron and what is the sign that it may occur

A

Ischemic colitis is a severe complication, and is indicated by a patient developing constipation (especially since the drug was given to a pt with diarrhea)

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3
Q

What drug class is lubiprostone

A

Selective chloride channel activator

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4
Q

What drug class is bisacodyl

A

Stimulant laxitive

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5
Q

What drug class is crofelemer

A

Chloride channel inhibitors

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6
Q

What conditions are treated with lubiprostone

A
  • IBS-C
  • chronic idiopathic constipation (CIC)
  • Opioid induced constipation (OIC)
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7
Q

What is castor oil hydrolized to

A

Ricinoleic acid

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8
Q

What drug class is alosetron

A

5 HT antagonists

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9
Q

What drug class is naloxegol

A

Opioid antagonist

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10
Q

What is the mechanism of action for guanylate cyclase G agonist

A

Increases cGMP leading so secretion of chloride and bicarbonate

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11
Q

Which patients need extra monitoring when on eluxadoline

A

Those without gallbladders at risk for pancreatitis

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12
Q

What drug class is glycerin

A

Stimulant laxitve

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13
Q

What drug class is dicylomine

A

Antimuscarinic

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14
Q

What drug class is chlordiazepoxide

A

Antimuscarinic

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15
Q

What is guanylate cyclase C agonists used to treat

A

Constipation

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16
Q

What is the drug class opioid agonists used to treat

A

Diarrhea

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17
Q

Which conditions are treated with Linaclotide

A

IBS- constipation

Chronic idiopathic constipation

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18
Q

What is the drug class 5HT antagonists used to treat

A

Diarrhea

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19
Q

What drug class is alvimopan

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A

Opioid antagonists

20
Q

What drug class is hyoscyamine

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A

Antimuscarinic

21
Q

What is the indication for eluxadoline

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A

IBS-diarrheal subtype (IBS-D)

22
Q

What drug class is methylnaltrexone

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A

Opioid antagonist

23
Q

What drug class is senna

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A

Stimulant laxitive

24
Q

What drug class is loperamide

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A

Opioid agonists

25
What is the source of crofelemer
Sap from croton lechleri
26
What is sodium picosulfate used for
Precolonoscopy
27
What is the drug class prostaglandin inhibators used to treat
Diarrhea
28
What is the mechanism of action of stimulants
Aka irritants and actually aggregate the lining to increase motility
29
What drug class is Eluxadoine
Opioid agonists
30
What is the complication seen with alvimopan
Risk of MI
31
What are the contraindications for eluxadoline
- Biliary tract infection and bile issues - Panceratic issues - liver failure - alcoholism
32
What are selective Chloride channel activators used to treat
Constipation
33
What drug class is castor oil
Stimulant laxitive
34
What are the side effects of treatment of antimuscarinic in IBS patients
Anticholinergic effects (DUMBBELLS)
35
What drug class is bismuth
Prostaglandin inhibators
36
What is the drug class chloride channel inhibitors used to treat
Diarrhea
37
When is alosetron used
Chronic sever, IBS-diarrheal is not responsive to other therapies (especially in women)
38
What drug class is clidinium
Antimuscarinic
39
What is the mechanism of action for lubiprostone
Increases the secretion by activating chloride channels CIC-2 in luminal epithelium
40
Which patients are given crofelemer
Non-infectious Diarrhea in HIV and AIDs patients with anti-retroviral therapy
41
When is Alvimopan used
Accelerating time in GI recovery following bowel surgery and prevention of ileus
42
What are the antimuscarinic agents given for
Abdominal pain/IBS
43
What drug class is linaclotide
Guanylate Cyclase C agonists
44
What must be given with diphenooxylate and what is the reasoning
Class 5 drug opiate, given with atropine for abuse potential
45
What drug class is calcium polycarbophil
Bulk forming cathartic

Pharmacology & Drugs (43 decks)

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