Neuro-Anesthetic Drugs

Question 1

What is the common use for benzocaine

Answer 1

Local anesthetic:

-Poor water solubility, so a topical cream for derm, hemorrhoids, premature ejaculation, anesthetic lubricant

Question 2

What is the common use for bupivacaine

Answer 2

Local anesthetic:

-long duration, usually for sensory block

Question 3

What is the common use for cocaine

Answer 3

Local anesthetic:

-bloackage of nerve impulses, topical in upper respiratory

Question 4

What is the common use for dibucaine

Answer 4

Local anesthetic:

-Toxic during injection, so topical cream only

Question 5

What is the common use for lidocaine

Answer 5

Local anesthetic:

-faster, more intense, longer lasting, and antiarrythmic

Question 6

What is the common use for procaine

Answer 6

Local anesthetic:

-Lower potently, longer onset, shorter duration, used only for infiltrate anesthesia

Question 7

Which local anesthetic drug can not be given with sulfonamide antibiotics

Answer 7

Procaine

Question 8

What is a major toxic side effect of halothane

Answer 8

Hepatitis (2 days to 3 weeks following exposure)

Question 9

What is a major side effect of enflurane

Answer 9

Renal toxicity (due to fluorinated metabolites)

Question 10

What is a major side effect of sevoflurane

Answer 10

Renal toxicity (due to fluoridated metabolites)

Question 11

What is the antidote for malignant hyperthermia

Answer 11

Dantrolene

Question 12

What are the properties of pharmokinetics of propofol

Answer 12

Metabolized in the liver very quickly, so fast onset and recovery

Question 13

What are the system effects of propofol

Answer 13

• Decrease in BP

- Respiratory depression

Question 14

What are the systemic effects of fospropofol

Answer 14

Same a propofol, but prolonged onset and recovery

Question 15

What are the method that etomidate is used for analgesia

Answer 15

Hypnotic, not analgesic

Question 16

What are the systemic effects of etomidate

Answer 16

• CV stability

- suppression of steroid production

Question 17

What are the characteristics seen in administration of ketamine

Answer 17

• Catatonia, amnesia, and analgesia

- with or without loss of consciousness

Question 18

What are the systemic effects seen by ketamine

Answer 18

• increased cerebral blood flow

- CV stimulator

Question 19

What class of drug is fentanyl

Answer 19

Opioid analgesic

Question 20

What class of drug is sufentanil

Answer 20

Opioid anesthetic

Question 21

What class of drug is remifentanil

Answer 21

Opioid analgesic

Question 22

What class of drug is morphine

Answer 22

Opioid anesthetic

Question 23

What class of drug is thopental

Answer 23

Barbiturate

Question 24

What class of drug is methohexital

Answer 24

Barbiturates

Question 25

What are the induction/recovery times, along with the the characteristics of Etomidate

Answer 25

Rapid onset, moderate recovery | -Provides CV stability, decreased steroidogensis and muscle movements

Question 26

What are the induction/recovery times, along with the the characteristics of ketamine

Answer 26

Moderate rapid onset/recovery | -CV stimulation and increased cerebral flow

Question 27

What are the induction/recovery times, along with the the characteristics of methohexital

Answer 27

Rapid onset and recovery | -Used for short ambulatory procedures

Question 28

What are the induction/recovery times, along with the the characteristics of midazolam

Answer 28

Slow onset and recovery | -balanced anesthetic, CV stability and amnesia

Question 29

What are the induction/recovery times, along with the the characteristics of propofol

Answer 29

Rapid onset and recovery | -antimemetic

Question 30

What are the induction/recovery times, along with the the characteristics of thiopental

Answer 30

Rapid onset and recovery (bolus dependent with slow recovery following IV) -CV depression

Question 31

Which population should thiopental be avoided in

Answer 31

Porphyria patients

Question 32

What are the induction/recovery times, along with the the characteristics of fentanyl

Answer 32

Slow onset and recovery | -analgesic

Question 33

What is the drug to reverse midazolam

Answer 33

Flumazenil

Question 34

What is the drug to reverse fentanyl

Answer 34

Naloxone