Ch. 30 Renal - Book/2 Flashcards

(58 cards)

1
Q

intrarenal/intrinsic AKI can result from

A

ischemic acute tubular necrosis ATN

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2
Q

prerenal AKI - poor perfusion can result from

5

A
  1. hypotension
  2. hypovolemia associated with hemorrhage or fluid loss i.e. burns
  3. sepsis
  4. inadequate CO i.e. MI
  5. renal vasoconstriction i.e. NSAIDs
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3
Q

what provide an index of renal function during the AKI recovery phase

A

plasma creatinine concentrations

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4
Q

AKI - prevention of injury is possible in which phase

A

initiation

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5
Q

renal failure refers to

A

significant loss of renal function

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6
Q

prevention of AKI involves avoidance of

3

A
  1. hypotension
  2. hypovolemia
  3. nephrotoxicity
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7
Q

postrenal AKI usually occurs with

A

UTO that affects the kidneys bilaterally

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8
Q

when less than 10% of renal function remains, this is termed

A

ESKD

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9
Q

AKI type - renal vasoconstriction i.e. NSAIDs

A

pre

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10
Q

anuria suggests

A

bilateral renal artery occlusion

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11
Q

caused by inadequate kidney perfusion

A

prerenal AKI

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12
Q

increased blood urea nitrogen levels and frequently increased serum creatinine levels

A

azotemia

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13
Q

rare AKI

A

post

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14
Q

what can serve as a measure of GFR (serum protein)

A

cystatin C

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15
Q

sudden decline in kidney function with a decrease in glomerular filtration and urine output with accumulation of nitrogenous waste products in the blood

A

AKI

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16
Q

interval when glomerular function returns but the regerating tubules cannot concentrate the filtrate

A

AKI recovery/polyuric phase

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17
Q

postrenal AKI causes an increase in intraluminal pressure upstream from the site of obstruction with gradual what

A

decrease in GFR

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18
Q

AKI maintenance phase is the period of

A

established kidney injury and dysfunction after initiating event has been resolved

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19
Q

renal insuff levels of serum creatinine and urea are

A

mildly elevated

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20
Q

AKI results from

4

A
  1. ischemic injury related to extracellular volume depletion
  2. ischemia from decreased renal blood flow
  3. toxic injury from chemicals
  4. sepsis-induced injury
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21
Q

AKI maintenance phase aka

A

oliguric phase

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22
Q

AKI phase in which reduced perfusion or toxicity in which kidney injury is evolving

A

initiation

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23
Q

anuria is uncommon in

A

ATN

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24
Q

AKI phases

A
  1. initiation
  2. maintenance
  3. recovery
25
intrarenal AKI aka
intrinsic
26
AKI phase where serum creatinine and blood urea nitrogen BUN increase
maintenance
27
AKI recovery phase aka
polyuric phase
28
type of renal failure that can occur after diagnostic catheterization of the ureters
postrenal AKI
29
mechanisms that contribute to oligura | 3
1. alterations in renal blood flow 2. tubular obstruction 3. tubular backleak
30
AKI pre renal aka
renal hypoperfusion
31
AKI initiation phase is the phase of
reduced perfusion or toxicity in which kidney injury is evolving
32
ESKD
<10% of renal function remains
33
can result from ischemic acute tubular necrosis ATN
intra AKI
34
intra AKI from ATN is related to | 6
1. prerenal AKI 2. nephrotoxic ATN 3. acute glomerulonephritis 4. vascular disease 5. allograft rejection 6. interstitial disease
35
a decline in renal function to about 25% of normal or a GFR of 25 to 30 ml/min
renal insufficiency
36
AKI is a
sudden decline in kidney function with a decrease in glomerular filtration and urine output with accumulation of nitrogenous waste products in the blood
37
AKI type - hypotension
pre
38
AKI type - hypovolemia
pre
39
uremia is a syndrome of renal failure and includes elevated what 2
1. blood urea | 2. blood creatinine
40
AKI accumulation of nitrogenous waste products in the blood is to 2
1. creatinine | 2. blood urea
41
most common reason for AKI
prerenal
42
AKI - urine output is lowest during which phase
maintenance
43
how much glomerular filtration must be lost before there is elevation of serum creatitine level
50%
44
prerenal AKI is caused by
inadequate kidney perfusion
45
AKI stands for
acute kidney injury
46
AKI phase where diuresis is common
AKI recovery
47
AKI type - shock
pre
48
AKI type - inadequate CO i.e. MI
pre
49
intra AKI - microcirculatory vasoconstriction occurs in response to
injury and inflammation
50
renal insufficiency refers to
a decline in renal function to about 25% of normal or a GFR of 25 to 30 ml/min
51
uremia is a syndrome of
renal failure
52
Cystatin C
serum protein freely filtered at the glumerulus, that can act as a measure of GFR
53
characteristic finding of postrenal AKI | 2
1. several hours or anuria | 2. flank pain with polyuria
54
AKI phase - established kidney injury and dysfunction
maintenance/oliguric phase
55
uremia is accompanied by | 6
1. fatigue 2. anorexia 3. nausea 4. vomiting 5. pruritus 6. neurologic changes
56
refers to significant loss of renal function
renal failure
57
azotemia is characterized by
increased blood urea nitrogen levels and frequently increased serum creatinine levels
58
AKI recovery/polyuric phase
interval when glomerular function returns but the regeneration tubules cannot concentrate the filtrate