Ch. 36 GI - Book/3 Flashcards

(41 cards)

1
Q

accumulation of ascitic fluid causes

3

A
  1. abdominal distention
  2. increased abdominal girth
  3. weight gain
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2
Q

what causes light colored stool

A

the complete obstruction of bile flow from the liver to the duodenum

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3
Q

causes of ascites include

6

A
  1. cirrhosis #1
  2. heart failure
  3. constrictive pericarditis
  4. abdominal malignancies
  5. nephrotic syndrome
  6. malnutrition
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4
Q

long term portal HTN problems include

5

A
  1. varices
  2. splenomegaly
  3. ascites
  4. hepatic encephalopathy
  5. hepatopulmonary syndrome
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5
Q

obstructive jaundice can result from

2

A

extrahepatic (post) or intrahepatic obstruction

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6
Q

partial obstruction of bile flow from liver to duodenum results in what stool

A

normal in color

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7
Q

jaundice in newborns is caused by

A

impaired bilirubin uptake and conjugation

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8
Q

obstruction of bile canaliculi can cause

A

intrahep obstructive jaundice

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9
Q

itching aka

A

pruritus

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10
Q

intrahep obstructive jaundice involves

2

A
  1. disturbances in hepatocyte function

2. obstruction of bile canaliculi

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11
Q

several factors contribute to the development of ascites

4

A
  1. portal HTN
  2. decreased synthesis of albumin by the liver
  3. splanchnic arterial vasodilation
  4. renal sodium and water retention
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12
Q

most common cause of portal HTN is

A

fibrosis and obstruction caused by cirrhosis of the liver

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13
Q

decreased bilirubin uptake or conjugation causes

A

unconjugated hyperbilirubinemia

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14
Q

disorders of bilirubin metabolism (unconjugated bilirubin) can be caused by
2

A
  1. drug induced

2. hereditary disorder

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15
Q

pruritis aka

A

itching

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16
Q

icterus aka

A

jaundice

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17
Q

hemolytic jaundice causes

A

hemolytic anemias i.e. sickle cell

18
Q

10% of people with ascites develop what

A

bacterial peritonitis

19
Q

hyperbilirubinemia and jaundice can result from

3

A
  1. extrahepatic (posthepatic) obstruction to bile flow
  2. intrahepatic obstruction
  3. prehepatic excessive production of unconjugated bilirubin
20
Q

portal HTN is caused by

A

disorders that obstruct or impede blood flow through any component of the portal venous system or vena cava

21
Q

hepatic encephalopathy results from a combo of

A

biochemical alterations that affect neurotransmission and brain function

22
Q

the complete obstruction of bile flow from the liver to the duodenum causes

A

light colored stool

23
Q

most common cause of ascites

24
Q

excessive hemolysis of RBC can cause

A

hemolytic jaundice (pre or nonobstructive)

25
portal HTN is
abnormally high BP in the portal venous system caused by resistance to blood flow
26
complications common to all liver disorders | 5
1. portal HTN 2. ascites 3. hepatic encephalopathy 4. jaundice 5. hepatorenal syndrome
27
abnormally high BP in the portal venous system caused by resistance to blood flow
portal HTN
28
extrahep obstructive jaundice develops if
the common bile duct is occluded
29
what accompanies jaundice because bilirubin accumulates in the skin
pruritus/itching
30
hepatic encephalopathy - ammonia cannot be converted to
urea
31
what lab evaluation establishes whether elevated plasma bilirubin is conjugated or unconjugated or both
serum levels
32
disorders that obstruct or impede blood flow through any component of the portal venous system or vena cava
portal HTN
33
ascites - portal HTN and reduced albumin levels cause
capillary hydrostatic pressure to exceed capillary osmotic pressure, pushing water into the peritoneal cavity
34
two common things that occlude bile duct
1. inflammation | 2. gallstone
35
jaundice is caused by
hyperbilirubinemia
36
portal HTN intrahepatic causes result from | 7
1. vascular remodeling with shunts 2. thrombosis 3. inflammation 4. fibrosis 5. biliary cirrhosis 6. viral hepatitis 7. schistosomiasis (parasitic infection)
37
portal HTN posthepatic causes occur from | 2
1. hepatic vein thrombosis | 2. cardiac disorders that impair the pumping ability of the right side of the heart
38
jaundice aka
icterus
39
bacterial peritonitis from ascites sx | 5
1. fever 2. chills 3. abdominal pain 4. decreased bowl sounds 5. cloudy ascitic fluid
40
sx from jaundice of viral of bacterial inflammation in the liver 3
1. fever 2. chills 3. pain
41
urine may be what, several days before the onset of jaundice
darker