Ch. 36 GI - Book/2 Flashcards

(58 cards)

1
Q

UC is less common in people who

A

smoke

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2
Q

CD and smoking

A

increases the risk for developing severe disease

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3
Q

sx of DD

5

A
  1. cramping of lower abdomen
  2. diarrhea
  3. constipation
  4. distention
  5. flatulence
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4
Q

risk factors and theories of cause of IBDs include

4

A
  1. genes
  2. environment
  3. alterations in epithelial cell barrier function
  4. altered immune response to intestinal microflora
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5
Q

most common areas for CD

2

A
  1. distal small intestine

2. proximal large colon

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6
Q
diverticular disease is associated with
3
-increased
-abnormal
-alterations
A
  1. increased intracolonic pressure
  2. abnormal neuromuscular function
  3. alterations in intestinal motility
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7
Q

what meds are used for tx of serious UC

3

A
  1. thioprine agents
  2. immunodulatory agents
  3. vedolizumad
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8
Q

idiopathic inflammatory disorder that affects any part of the GI tract from mouth to anus

A

CD

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9
Q

rectum aka

A

proctitis

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10
Q

diverticula

A

herniations or saclike outpouchings of the mucosa and submucosa through the muscle layers in the sigmoid colon

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11
Q

uncomplicated DD is tx with

2

A
  1. bowel rest

2. analgesia

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12
Q

imaging of the small intestine is used in dx what

A

CD

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13
Q

complicated diverticulitis includes

5

A
  1. abscess
  2. fistula
  3. obstruction
  4. bleeding
  5. perforation
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14
Q

what often relieves symptoms of DD

2

A
  1. increase fiber

2. probiotics

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15
Q

DD common associated finding is

A

thickening of the circular muscles and shortening of the longitudinal muscles surrounding the diverticula

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16
Q

what may cause large amounts of watery diarrhea in UC

2

A
  1. loss of absorptive mucosal surface

2. rapid colonic transit time

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17
Q

effective for initial therapy for CD

A

immunomodulatory (anti-TNF)

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18
Q

UC mucosal destruction and inflammation causes

3

A
  1. bleeding
  2. cramping pain
  3. urge to defecate
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19
Q

most common sx of CD

A

diarrhea

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20
Q

chronic inflammatory disease that causes ulceration of the colonic mucosa

A

UC

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21
Q

asymptomatic diverticular disease

A

diverticulosis

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22
Q

diverticulosis is

A

asymptomatic diverticular disease

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23
Q

UC that involve the entire colon sx

7

A
  1. abdominal pain
  2. fever
  3. elevated pulse rate
  4. frequent diarrhea
  5. urgency
  6. bloody stool
  7. crampy pain
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24
Q

what type of stool is common in UC

A

frequent diarrhea with passage of small amounts of blood and purulent mucus

25
CD aka | 3
1. granulomatous colitis 2. ileocolitis 3. regional enteritis
26
diverticula most common location
sigmoid colon
27
bleeding and cramping pain from anus
UC
28
UC complications include | 3
1. fissures 2. hemorrhoids 3. perirectal abscess
29
chronic relapsing IBDs | 2
UC | CD
30
component of therapy for CD
stop smoking
31
predisposing factors for DD | 7
1. older age 2. genes 3. obesity 4. smoking 5. diet 6. lack of physical activity 7. medications (aspirins)
32
if the diverticula become inflamed or abscesses form, what can develop 3
1. fever 2. leukocytosis 3. tenderness of the LLQ
33
CD typical lesion is a
granuloma with a cobblestone appearance
34
most common site for skip lesions of CD | 2
1. ascending colon | 2. transverse colon
35
urge to defecate is to
UC
36
sx of CD | 4
1. diarrhea 2. rectal bleeding 3. weight loss 4. abdominal pain
37
UC
chronic inflammatory disease that causes ulceration of the colonic mucosa
38
diverticula can occur where
anywhere in GI tract, particularly in weak points in the colon wall
39
CD inflammation begins and spread with
begins in the intestinal submucosa and spreads with discontinuous transmural involvement (skip lesions)
40
if CD involved the ileum what may the patient be
anemic as a result of malabsorption of vitamin B12
41
frequent diarrhea with small amounts of blood and purulent mucus
UC
42
UC common location | 2
rectum | sigmoid colon
43
UC mucosa is
hyperemic and may appear dark red and velvety
44
UC mild to mod disease is tx with | 2
5-aminosalicyclate therapy followed by steroids
45
definitive tx for CD
none
46
hypoalbuminemia is a sx of
CD
47
the primary lesion of UC begins with
inflammation at the base of the crypt of Lieberkuhn in the large intestine
48
biomarkers for CD
none
49
CD
idiopathic inflammatory disorder that affects any part of the GI tract from mouth to anus
50
herniations or saclike outpouchings of the mucosa and submucosa through the muscle layers in the sigmoid colon
diverticula
51
UC lesions appear around what age
20-40 yrs old
52
the course of UC consists of
intermittent periods of remission and exacerbation
53
what medications can cause DD | 2
1. aspirin | 2. non-steroidal anti inflammatory drugs
54
CD - fistulae may form in the
perianal area
55
ulcerations of CD can produce
fissures that extend inflammation into lymph tissue
56
diverticulitis
represents inflammation
57
cause of diverticular disease is
unknown
58
disease begins in the rectum and extends proximally to the entire colon
UC