Flashcards in CNS Part 2 Deck (20):
neurosyphilis is caused by the invasion of what organism into CNS?
What is a result of damage to sensory nerves (demyelination) in dorsal roots that produces ataxia, loss of pain, and proprioception?
what type of syphilis involves base of brain and may result in cranial nerve palsies?
neurosyphilis results in formation of meningeal granulomas known as?
several hours after treatment of syphilis, pt can undergo febrile reaction called
which organism can have Jarisch-Herkheimer reaction?
Progressive multifocal leukoencephalopathy (PML) caused by what?
demyelinating disease caused by JC virus (member of polyomavirus)
Rare complication of measles (rubeola)
subacute sclerosing panencephalitis
how do you diagnose subacute sclerosing pan encephalitis (SSPE)
CSF has Rubeola IgG ab
what disease is neurotropic, destroying the motor neurons in anterior horn of brainstem and leading to flaccid paralysis?
rabies virus is what type of disease
how does rabies virus travel?
via peripheral nerves from site of bite to brain (1-3 months)
how do you dx rabies
with brain biopsy after patient dies (Aaaahhhh)
... or you can do a PCR saliva, urine, or CSF
what is 100% diagnostic of rabies but only found in 20% of cases?
HIV causes what type of dementia?
AIDs dementia complex (ADC) is a later disease process
- CD4 cell count decrease tells you it is later stage
etiology of AIDS dementia complex
macrophages carry HIV to brain and release toxins which leads to cell death and dementia
gross change in brain tissue with dementia
often fatal encephalopathy with vomitting, fatty infiltration of liver, and swelling of kidneys and brain
What is Reye's syndrome associated with
treating a previous viral infection such as influenza or chicken pox with aspirin