CNS Part 2 Flashcards Preview

Path IV Quizzes > CNS Part 2 > Flashcards

Flashcards in CNS Part 2 Deck (20):
1

neurosyphilis is caused by the invasion of what organism into CNS?

treponema pallidum

2

What is a result of damage to sensory nerves (demyelination) in dorsal roots that produces ataxia, loss of pain, and proprioception?

Tabes dorsalis

3


what type of syphilis involves base of brain and may result in cranial nerve palsies?

meningovascular syphilis

4

neurosyphilis results in formation of meningeal granulomas known as?

gummas

5

several hours after treatment of syphilis, pt can undergo febrile reaction called

Jarisch-Herkheimer reaction

6

which organism can have Jarisch-Herkheimer reaction?

neurosyphilis

7

Progressive multifocal leukoencephalopathy (PML) caused by what?

demyelinating disease caused by JC virus (member of polyomavirus)

8

Rare complication of measles (rubeola)

subacute sclerosing panencephalitis

9

how do you diagnose subacute sclerosing pan encephalitis (SSPE)

CSF has Rubeola IgG ab

10

what disease is neurotropic, destroying the motor neurons in anterior horn of brainstem and leading to flaccid paralysis?

polio

11

rabies virus is what type of disease

zoonotic

12

how does rabies virus travel?

via peripheral nerves from site of bite to brain (1-3 months)

13

how do you dx rabies

with brain biopsy after patient dies (Aaaahhhh)
... or you can do a PCR saliva, urine, or CSF

14

what is 100% diagnostic of rabies but only found in 20% of cases?

negri bodies

15

HIV causes what type of dementia?

AIDs dementia complex (ADC) is a later disease process
- CD4 cell count decrease tells you it is later stage

16

etiology of AIDS dementia complex

macrophages carry HIV to brain and release toxins which leads to cell death and dementia

17

gross change in brain tissue with dementia

atrophy

18

often fatal encephalopathy with vomitting, fatty infiltration of liver, and swelling of kidneys and brain

Reye's syndrome

19

What is Reye's syndrome associated with

treating a previous viral infection such as influenza or chicken pox with aspirin

20

infection of brain with vacuolated areas due to prion

spongiform encephalopathy
- Kuru
- Creutzfeldt-Jakob disease (CJD)