Quiz 1 Female Flashcards Preview

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Flashcards in Quiz 1 Female Deck (69):
1

hist of psoriasis of vulva

elongation/increased depth of rete ridges
hyperkeratosis
parakeratosis
loss of granular layer
vascular dilation

2

What are the 3 aspects of psoriasis?

1) Kebners phenomenon: lesions that occur after trauma.
2) Asuspitz sign
3) Blanching around lesions in skin

3

Lichen simplex chronicus

scratch itch scratch cycle
thickened epithelium

4

hist of lichen planus

saw tooth rete ridges
leukocytes

5

Lichen sclerosis

- thickening of skin of vulva and peri-anal area
- appears pale/white

6

What % of pt with lichen sclerosis will develop cancer?

5%

7

hist of lichen sclerosis?

- rete ridges disappear
- atrophy
- lymphocytes
- edematous degeneration of basal layer

8

hist of lichen simplex chronicus

thickening of rete ridges
thickened epithelium
hyperkeratosis

9

what virus causes moloscum contagiousum?

pox virus

10

how do you distinguish lesions of moloscum contagiousum?

umbilicated

11

If lesions of many conditions look the same, how do you distinguish?

Biopsy to look at rete ridges

12

#1 bacteria to cause bartholins duct cysts?

e. coli

13

hist of HSV 2?

multinucleate giant cell

14

what strains of HPV cause genital warts?

6 and 11

15

what strains of HPV cause CA?

16 and 18 (31 and 45 less common)

16

what do you call a genital wart?

condyloma acuminata

17

does a bartholin cysts = STI?

no

18

what is actual name of syphilis?

treponema pallidum

19

what is a painless ulcer? what causes it?

chancre
syphilis (treponema pallidum)

20

his of syphilis

gm -
spirochete

21

what is a flat wart? what causes it?

condyloma latum
syphilis

22

hist of condyloma acuminata

acanthosis
hyperkeratosis
cytoplasmic vacuolation

23

discharge of BV

thick, creamy, noxious smell (fishy)

24

discharge of trichomonas

foamy, noxious smell

25

candida discharge

non-noxious smell

26

most common vaginal infection? what causes it?

BV
gardeneralla and bacteroides

27

what is second most common vaginal infection?

candida

28

criteria to dx BV?

- fishy oder
- increased pH
- sticky, thick, white d/c
- clue cells (appear shimmering)

29

gonorrhoeae

gm -
diplococci
looks like 2 kidney beans
extracellular and intracellular

30

chlamydia trachomatis

intracellular
infected cells look pink
red, friable cervix

31

third most common vaginal infection

trichomonas: flagellated protazoa

32

vulvar intraepithelial neoplasia (VIN)

significant variety of colored plaques (hyper pigmentation)

33

hist of VIN

basiloid and warty cells
or well differentiated cells

34

if warty and basiloid cells of VIN, what is it associated with?

HPV 16 and 18

35

which form of cells indicates more aggressive VIN?

well-differentiated
(not associated with HPV)

36

most common vulvar CA

SCC

37

most common vulvar CA

SCC

38

what is adenocarcinoma of vagina linked to?what is it called?

mother who was treated with DES
clear cell adenocarcinoma

39

hist of clear cell adenocarcinoma

vacuolated tumor cells in clusters
gland like structures
nuclei look clear

40

risks for cervical ca

early age of first intercourse
multiple sexual partners
persistent infection of high risk HPV
presence of cancer associated HPV strains
exposure to oral contraceptives
tobacco use
history of chlamydia or others
multiple births

41

koilocytosis

large nuclei that stain dark with halo
HPV associated
ASC-US or atypical squamous cells

42

endometriosis

endometrial tissue outside uteran cavity

43

where is #1 location for endometriosis?

ovaries

44

what cause infertility in endometrial pt

scar formation, adhesions, anatomical distortions of involved ovary, fallopian tubes, or uterus
inflammation

45

endometrioma

chocolate cyst
ovarian cyst from ectopic endometrial tissue that bleeds within ovary

46

adenomyosis

endometrial tissue in muscle wall of myometrium of uterus

47

endometritis

infection or inflammation of endometrium
caused by retaining pieces of placenta or infections or PID

48

acute endometritis

micro-abscesses or neutrophils within endometrial glands
most are poly-microbial

49

chronic endometritis

presence of plasma cells in stroma
doesn't respond to antibiotics
eccentric nucleus (off to one side)

50

most common location of PID

ovaduct/fallopian tube

51

sequelae of PID

scarring of fallopian tube
rate of ectopic pregnancy increases 6-10 fold
tubo-ovarian abscess
salpingo-oophoritis with tubo-ovarian abscess

52

Atypical hyperplasia

estrogen dominant state
persistent hyperplasia has high likelihood of becoming malignant

53

Most common gynocologic cancer in US

endometrial ca

54

most common type of endometrial ca? who gets it?

adenocarcinoma
post-menopausal women

55

risk factors for endometrial ca

nulliparity
obesity
hyperglycemia
DM
HTN

56

most common type of endometrial cancer

adenocarcinoma

57

leiomyoma

fibroid
benign smooth muscle tumor of uterus
whorled pattern of smooth muscle

58

malignant leiomyoma and hist

leiomyosarcoma
hyperchromatic
deeply staining nuclei
more pleomorphism
irregular nucleus

59

most common endocrine disorder in females and cause

PCOS
- caused by excessive androgenic hormones like testosterone which is stimulated by excess LH from ant pit

60

PCOS on imaging looks like?

string of pearls

61

PCOS related to?

DM
insulin resistance
hyperglycemia
obesity

62

serous cyst adenoma

benign epithelial tumors of ovary that can become very big
single celled lining like fallopian tube

63

mucinous cyst adenoma

single cell layer of mucin
similar to endocervix

64

ovarian ca

psammoma body: small calcification stains pink/purple staining
- also found in other conditions

65

ovarian serous cystadenocarcinoma is characterized by what?

psammoma body: small rounded, purple staining calcification
- also found in other conditions

66

what is the difference between acute and chronic endometritis?

acute: micro-abscesses or neutrophils within endometrial glands
chronic: plasma cells in stroma
- doesn't respond to antibiotics

67

what is the difference between acute and chronic endometritis?

acute: micro-abscesses or neutrophils within endometrial glands
- polymycrobial
chronic: plasma cells in stroma
- doesn't respond to antibiotics

68

what infection is most commonly linked with chronic endometritis?

PID

69

20% of endometrial cancers which type? Notable for what?

- papillary serous carcinoma
- accumulation of p53 protein