Flashcards in Quiz 3 Adrenals Deck (22):
What are the 3 zones of the adrenal cortex what does each secrete?
zona glomerulosa: mineralcorticoids (aldosterone)
zona fasciculata: glucocorticoids (cortisol)
zona reticularis: sex hormones (DHEA)
what does the adrenal medulla secrete?
#1 cause of primary hyperaldosteronism/Conn's syndrome?
functional adrenal adenoma
HTN + unexplained hypokalemia and hypernatremia, high serum aldosterone, decreased plasma renin
primary hyperaldosteronism/Conn's syndrome
#1 iatrogenic cause of Cushing's
#1 non-iatrogenic cause of Cushing's
tumors in pituitary (cushing dz) tumors in adrenal gland (cushing syndrome)
#1 cause of primary Addison's disease
autoimmune disease of adrenal cortex
Primary Addison's pigmentation
high ACTH leads to hyperpigmentation
#1 cause of secondary Addison's disease
Inadequate secretion of ACTH by anterior pituitary
Secondary Addison's pigmentation
low ACTH leads to no hyperpigmentation
Which type of Addison's has high ACTH?
What can happen with withdrawal of long-term exogenous corticosteroid use?
Adrenal gland failure due to hemorrhage into adrenal glands
#1 bacterial cause of Waterhouse-Fredrickson sydrome
Miningococcus (neisseria meningitidis)
#1 cause of congenital adrenal hyperplasia due to
what labs are elevated in 21 hydroxyls deficiency
#1 pathology associated with adrenal medulla
Catecholemine secreting tumor of chromatin cells within adrenal medulla
#1 solid extra-cranial malignancy in infants and children
tumor of neural crest cells, usually arise form adrenal glands but can be located anywhere on sympathetic chain
Rosettes (circular groupings of dark tumor cells surrounding a pale center of neurofibrils)