Quiz 3 Parathyroid Flashcards Preview

Path IV Quizzes > Quiz 3 Parathyroid > Flashcards

Flashcards in Quiz 3 Parathyroid Deck (19):
1

light to dark pink, eosinophilic, polygonal, central, round nucleus contains secretory granules

chief cells

2

what do chief cells located in parathyroid gland secrete?

PTH

3

what type of cells are few in number, smaller nuclei.

oxyphil cells (don't know what they secrete)

4

What hormone decreases serum calcium?

calcitonin

5

what cells secrete calcitonin?

parafollicular cells of thyroid gland

6

PTH1 receptors are where?

bone and kidney

7

PTH effects kidneys how?

increases renal tubular Ca reabsorption and phosphate excretion
converts vit D to active form

8

how does PTH effect bone?

increase Ca and phosphate reabsorption in intestine Ca
Ca>PO4

9

how does vit D effect Ca?

increases serum Ca and PO4 reabsorption in intestine
Ca>PO4

10

#1 cause of primary hyperparathyroid outpatient and overall

parathyroid adenoma

11

#1 cause of primary hyperparthyroid inpatient?

parathyroid carcinoma

12

single mass in parathyroid gland, identical appearing cell population, no adipose tissue, no mitotic figures

parathyroid adenoma

13

#1 cause of secondary hyperparathyroid

renal failure

14

reduced adipose tissue in parathyroid gland, but all cell types still present

primary hyperplasia (seen in secondary hyperparthyroid due to renal failure)

15

abrupt onset of hypercalcemic related symptoms (bone pain, renal stones)

parathyorid carcinoma

16

nests of neoplastic cells, not pleomorphic, with bands of fibrous stroma in between

parathyroid carcinoma

17

#1 cause of hypercalcemia of malignancy

ectopic production of PTHrP by CA cells

18

#2 most common CA that produces PTHrP

breast and lung

19

what do chief cells produce?

PTH