Quiz 3 Thyroid Flashcards Preview

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Flashcards in Quiz 3 Thyroid Deck (30):
1

what cells secrete calcitonin?

c-cells in colloid of thyroid

2

TSH level in hypothyroid?

increased

3

#1 cause of hypothyroid in US?

Hashimoto's

4

#1 cause of hypothyroid worldwide?

iodine deficiency

5

High TSH, low T3/T4

hypothyroid

6

#1 cause of hyperthyroid in US and WW?

Graves

7

#2 cause of hyperthyroid?

pituitary dysfunction

8

What are the antibodies in epithelial cells in Hoshimoto's?

anti-microsomal ab and anti- TPO ab

9

What are the antibodies in colloid of Hoshimotos?

anti-thyroglobulin ab

10

lymphocytic infiltration and fibrosis, no tissue hypertrophy, lymphocytes aggregate around colloid, and may see Hurthle cells?

hashimotos

11

Why do you need iodine for thyroid function?

To produce thyroxine

12

enlarged epithelial cells that stain pink with abundant eosinophilic granular cytoplasm due to altered mitochondria?

Hurthle cell

13

Where do you see Hurthle cells?

Hashimoto's, follicular thyroid CA

14

Granulomas and multinucleate giant cells in colloid of thyroid?

DeQuervain's Subacute Thyroiditis

15

#1 congenital neck malformation

thyroglassal duct cyst

16

#1 location of thyroglossal duct cyst

between isthmus and hyoid bone

17

#1 thyroid ca

papillary carcinoma

18

follicles irregularly enlarged and surrounded by flattened epithelium, associated with lack of increased thyroid activity

non-toxic multinodular goiter

19

marked hypercellularity consistent with hyper functioning thyroid

toxic nodular goiter/toxic thyroid nodule

20

What ab are present in Graves disease?

anti-LATS ab

21

hyper plastic epithelium, prominent scalloped colloid, tall columnar epithelium

Grave's

22

cold nodules on thyroid scan?

colloid cysts

23

well encapsulated, like normal tissue, follicles containing colloid with variability in size

follicular adenoma

24

are the majority of thyroid cancers malignant and unresponsive to therapy?

No, majority are benign and responsive to treatment

25

risk factors for papillary carcinoma?

female
hx of neck irradiation
young

26

prognosis for papillary carcinoma of thyroid is worse in what population?

elderly

27

frondlike tissue with fibrovascular core?

papillary carcinoma

28

what other tumors contain psamomma bodies?

ovarian papillary cystadenocarcinoma
prolactinoma

29

proliferation of parafollicular cells and lots of calcitonin in serum, pink hyaline material that looks like amyloid

medullary carcinoma

30

most malignant thyroid cancer?

undifferentiated/anaplastic