Flashcards in Quiz 3 Thyroid Deck (30):
what cells secrete calcitonin?
c-cells in colloid of thyroid
TSH level in hypothyroid?
#1 cause of hypothyroid in US?
#1 cause of hypothyroid worldwide?
High TSH, low T3/T4
#1 cause of hyperthyroid in US and WW?
#2 cause of hyperthyroid?
What are the antibodies in epithelial cells in Hoshimoto's?
anti-microsomal ab and anti- TPO ab
What are the antibodies in colloid of Hoshimotos?
lymphocytic infiltration and fibrosis, no tissue hypertrophy, lymphocytes aggregate around colloid, and may see Hurthle cells?
Why do you need iodine for thyroid function?
To produce thyroxine
enlarged epithelial cells that stain pink with abundant eosinophilic granular cytoplasm due to altered mitochondria?
Where do you see Hurthle cells?
Hashimoto's, follicular thyroid CA
Granulomas and multinucleate giant cells in colloid of thyroid?
DeQuervain's Subacute Thyroiditis
#1 congenital neck malformation
thyroglassal duct cyst
#1 location of thyroglossal duct cyst
between isthmus and hyoid bone
#1 thyroid ca
follicles irregularly enlarged and surrounded by flattened epithelium, associated with lack of increased thyroid activity
non-toxic multinodular goiter
marked hypercellularity consistent with hyper functioning thyroid
toxic nodular goiter/toxic thyroid nodule
What ab are present in Graves disease?
hyper plastic epithelium, prominent scalloped colloid, tall columnar epithelium
cold nodules on thyroid scan?
well encapsulated, like normal tissue, follicles containing colloid with variability in size
are the majority of thyroid cancers malignant and unresponsive to therapy?
No, majority are benign and responsive to treatment
risk factors for papillary carcinoma?
hx of neck irradiation
prognosis for papillary carcinoma of thyroid is worse in what population?
frondlike tissue with fibrovascular core?
what other tumors contain psamomma bodies?
ovarian papillary cystadenocarcinoma
proliferation of parafollicular cells and lots of calcitonin in serum, pink hyaline material that looks like amyloid