CV 4 BP Flashcards

(42 cards)

1
Q

Stroke volume calc

Normal number

A

LVEDV- LVESV

70 ml

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2
Q

CO calc and normal

A

SV x HR

5 LPM

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3
Q

EF calc and normal

A

SV/LVEDV

55-70%

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4
Q

PP Calc and normal

A

SBP-DBP

40

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5
Q

MAP calc 3 ways and normal

A

CO x SVR

1/3 SBP + 2/3 DBP

DBP + 1/3PP

93

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6
Q

Factor that controls heart rate

What 2 things affected by increased HR

A

Chronotropic

CO and BP increase

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7
Q

What factor controls contractility

If it increases, what increases leading 2 two more things increasing

A

Inotropic

EF increases which leads to increased CO and BP

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8
Q

SVR leads to ___ decreasing and ___ increasing

A

CO

BP

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9
Q

CVP increase leads to ___ increase, which leads to ___ increasing, and __ and __ increasing

A

LVEDV
SV
CO and BP

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10
Q

What polycythemia and anemia do to blood

A

Poly makes it harder to push blood, more resistance

Anemia makes it easier to push blood

Both from viscosity

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11
Q

Viscosity affect which factor of blood pressure

A

Peripheral resistance

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12
Q

What happens to HR and which system controls it when BP increases and decreases

A

Increases- heart rate lowers from PNS

Decreases- heart rate increases from SNS

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13
Q

What bainbridge reflex does

A

RAP stretch, atrial receptors stimulated, heart rate increases

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14
Q

What baroreceptor reflex does

A

Increased RAP increases CO and BP. Decrease HR

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15
Q

What happens to HR when we inhale and exhale

A

Inhale goes up

Exhale goes down

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16
Q

Intrapleural pressure is always ___

While inhaling it becomes

While exhaling it becomes

A

Negative

More negative

Less negative, more positive

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17
Q

How ventilation affects intrapleural pressure

A

Open lungs with pressure, pressure will be positive

18
Q

What more pressure in intrapleural space does to heart

A

Compresses atria and increases CVP

19
Q

Increase in preload does what to SV and CO

A

Increases both

20
Q

How to increase stroke volume without contractility

A

Greater preload
More crossbridges
Optimal overlap
More crossbridges from more calcium

21
Q

What has little effect on contractility

22
Q

What cant be directly equated to contractility

A

Force of contraction

23
Q

What 7 things affect contractility

A
SNS
Hormones
Failure 
Conditioning 
Ischemia 
Infarction
24
Q

What happens to CVP with SNS stim

What happens to cvp with volume loss and how it compensates

A

Increases

Decreases quickly, compensate with vasoconstriction of veins

25
How arteriole can control getting blood
Decides for itself, releases ACE/Ang II and endothelin to vasoconstrict
26
Tissue blood flow Who gets most 2 Which vital organs get most What doesnt get a lot at rest
Liver and kidney- filter blood Heart and brain, brain gets less than heart per mass Muscle
27
3 means of local control of blood flow
Metabolic regulation Autoregulation/myogenic regulation Shear stress induced vasodilation
28
Metabolic regulation of flow controls what and not what
Precapillary sphincter, not arteriole
29
What autoregulation does
Arterial bp high or low, brain wants and needs constant blood flow Smooth muscle arterioles constrict when they see high pressure and maintain same flow
30
How shear stress affects vascular smooth muscle
Blood going faster, feel more shear stress. Translated into NO which causes vessel to relax and get more NO
31
Where baroreceptors are located and what they respond to
Wall of aortic arch, vagus nerve Carotid sinus, glossopharyngeal nerve Changes in stretch
32
ANP and BNP do what
Tell kidney to dump sodium, decreases overall fluid volume because water follows
33
Vasopressin action
Vasoconstrictor released from posterior pituitary
34
Ang II effect
Vasoconstriction made from renin and ace action on angiotensin
35
Endothelin action
Vasoconstrictor released on endothelium
36
Epinephrine action and released by what
Vasoactive and cardioactive, adrenal medulla. Constriction and increased BP
37
ANP action and released by what
Dilator released by heart, causes na loss
38
3 vasoactive humoral regulators that affect BP in long run
Ang II Vasopressin ANP
39
Vasoconstrictors | 3
Norepi Ang II Vasopressin
40
Vasodilator 2
Bradykinin and histamine
41
3 things that work in seconds to minutes to regulate BP
Baroreceptors Chemoreceptors Cns ischemic response
42
Things with intermediate speed to regulate bp
Capillary shift | Renal blood volume