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Flashcards in CV 4 BP Deck (42):
1

Stroke volume calc

Normal number

LVEDV- LVESV

70 ml

2

CO calc and normal

SV x HR
5 LPM

3

EF calc and normal

SV/LVEDV
55-70%

4

PP Calc and normal

SBP-DBP
40

5

MAP calc 3 ways and normal

CO x SVR

1/3 SBP + 2/3 DBP

DBP + 1/3PP

93

6

Factor that controls heart rate

What 2 things affected by increased HR

Chronotropic

CO and BP increase

7

What factor controls contractility

If it increases, what increases leading 2 two more things increasing

Inotropic

EF increases which leads to increased CO and BP

8

SVR leads to ___ decreasing and ___ increasing

CO
BP

9

CVP increase leads to ___ increase, which leads to ___ increasing, and __ and __ increasing

LVEDV
SV
CO and BP

10

What polycythemia and anemia do to blood

Poly makes it harder to push blood, more resistance

Anemia makes it easier to push blood

Both from viscosity

11

Viscosity affect which factor of blood pressure

Peripheral resistance

12

What happens to HR and which system controls it when BP increases and decreases

Increases- heart rate lowers from PNS

Decreases- heart rate increases from SNS

13

What bainbridge reflex does

RAP stretch, atrial receptors stimulated, heart rate increases

14

What baroreceptor reflex does

Increased RAP increases CO and BP. Decrease HR

15

What happens to HR when we inhale and exhale

Inhale goes up

Exhale goes down

16

Intrapleural pressure is always ___

While inhaling it becomes

While exhaling it becomes

Negative

More negative

Less negative, more positive

17

How ventilation affects intrapleural pressure

Open lungs with pressure, pressure will be positive

18

What more pressure in intrapleural space does to heart

Compresses atria and increases CVP

19

Increase in preload does what to SV and CO

Increases both

20

How to increase stroke volume without contractility

Greater preload
More crossbridges
Optimal overlap
More crossbridges from more calcium

21

What has little effect on contractility

PNS

22

What cant be directly equated to contractility

Force of contraction

23

What 7 things affect contractility

SNS
Hormones
Failure
Conditioning
Ischemia
Infarction

24

What happens to CVP with SNS stim

What happens to cvp with volume loss and how it compensates

Increases

Decreases quickly, compensate with vasoconstriction of veins

25

How arteriole can control getting blood

Decides for itself, releases ACE/Ang II and endothelin to vasoconstrict

26

Tissue blood flow

Who gets most 2
Which vital organs get most
What doesnt get a lot at rest

Liver and kidney- filter blood
Heart and brain, brain gets less than heart per mass
Muscle

27

3 means of local control of blood flow

Metabolic regulation

Autoregulation/myogenic regulation

Shear stress induced vasodilation

28

Metabolic regulation of flow controls what and not what

Precapillary sphincter, not arteriole

29

What autoregulation does

Arterial bp high or low, brain wants and needs constant blood flow

Smooth muscle arterioles constrict when they see high pressure and maintain same flow

30

How shear stress affects vascular smooth muscle

Blood going faster, feel more shear stress. Translated into NO which causes vessel to relax and get more NO

31

Where baroreceptors are located and what they respond to

Wall of aortic arch, vagus nerve

Carotid sinus, glossopharyngeal nerve

Changes in stretch

32

ANP and BNP do what

Tell kidney to dump sodium, decreases overall fluid volume because water follows

33

Vasopressin action

Vasoconstrictor released from posterior pituitary

34

Ang II effect

Vasoconstriction made from renin and ace action on angiotensin

35

Endothelin action

Vasoconstrictor released on endothelium

36

Epinephrine action and released by what

Vasoactive and cardioactive, adrenal medulla. Constriction and increased BP

37

ANP action and released by what

Dilator released by heart, causes na loss

38

3 vasoactive humoral regulators that affect BP in long run

Ang II
Vasopressin
ANP

39

Vasoconstrictors
3

Norepi
Ang II
Vasopressin

40

Vasodilator 2

Bradykinin and histamine

41

3 things that work in seconds to minutes to regulate BP

Baroreceptors
Chemoreceptors
Cns ischemic response

42

Things with intermediate speed to regulate bp

Capillary shift
Renal blood volume