Development of the nervous system Flashcards Preview

Neuroscience > Development of the nervous system > Flashcards

Flashcards in Development of the nervous system Deck (50)
Loading flashcards...
1

Which of the three germ layers does the nervous system arise from?

Ectoderm

2

Which structure that arises in the ectoderm forms the basis of the nervous system?

Neural plate

3

What happens to the neural plate once it starts to develop?

Starts to invaginate/fold > forms tube beneath ectoderm

4

What is the tube that forms beneath the ectoderm when the neural plate invaginates known as?

Neural groove

5

Where does the neural groove lie in relation to the notochord?

Neural groove is above notochord

6

What happens to the neural groove after it begins to form?

Deepens > edges come together and join in midline > creates a tubular structure that can break free from overlying ectoderm

7

What is the tubular structure formed from the folding of the neural groove called?

Neural tube

8

How is the neural tube formed?

Neural groove deepens > edges come together and join in midline > creates a tubular structure that can break free from overlying ectoderm

9

What is the first physical structure of the nervous system to form?

Neural tube

10

Describe the neural tube?

Simple tube Single cell thick

11

What does the neural tube go on to form?

Brain and spinal cord

12

What does the hole in the neural tube go on to form?

Ventricular system

13

What does the ventricular system arise from?

Hole in the neural tube

14

Describe the gradient that exists in the neural tube?

Rostral to caudal gradient

15

What is the consequence of the rostral to caudal gradient in the neural tube?

Development occurs faster at the head end and slower at the tail end Rostral end is older

16

Describe the order of neural tube closure?

Closure tends to start towards middle, and leave ends of neural tube open

Zippers shut up and down from that midpoint

 

 

17

Gove examples of birth defects that arise as a result of failure of closure of the neural tube?

Spina bifida 

Anencephaly

18

Are the five 'zipping' processes in the closure of the neural tube dependent on each other?

No, largely indepedent

19

Briefly describe the segmentation process of the neural tube?

Rostral end of tube starts to well

3 distinct vesicles form

Further segmentation of these vesicles occurs 

20

Name the three vesicles initially formed by the segmetation of the neural tube? Which brain structure does each vesicle correspond to?

Prosencephalon (forebrain)

Mesencephalon (midbrain)

Rhombencephalon (hindbrain) 

21

What does the prosencephalon further divide into?

Telencephalon and diencephalon 

22

What does the rombencephalon further didvide into?

Seven segments (r1-r7)

 

23

Whathappens to the part of the neural tube that does not become segmented?

Intact neural tube goes on to form spinal cord

24

What do the pons and cerebellum arise from?

Metencephalon division of rhombencephalon 

25

What does the medulla arise from?

Myelencephalon division of rhombencephalon

26

What are the major derivatives of the telencephalon?

Cortex, basal ganglia, hippocampus

27

What are the major derivatives of the diencephalon?

Thalamus and hypothalamus

28

What does the caudal part of the neural tube go on to form?

Spinal cord

29

Describe the structure of the developing brain after neural tube segmentation has occured?

series of thin-walled bubbles

30

What is the neural crest?

cells tha lie between the neural groove and neural tube after the neural tube forms