JAALAS 2010 No. 5 KD

Question 1

Schuler et al. Measurement of Fetal Biparietal Diameter in Owl Monkeys .What is the genus and species or the owl monkey?

Answer 1

Aotus nancymaae

Question 2

Which of the following harbor cercopithicine herpesvirus 1?

a. Pan troglodytes
b. Macaca fascicularis
c. Aotus nancymaae
d. Saguinus Oedipus

Answer 2

b. Macaca fascicularis

Question 3

What is the gestation of the owl monkey?

a. 143-146 days
b. 60-63 days
c. 132-135 days
d. 152-155 days

Answer 3

c. 132-135 days

Question 4

Arbona et al. Treatment and Eradication of Murine Fur Mites.What is the most common genus/species of fur mite in murine colonies

Answer 4

Myobia musculi and Myoptes musculinus

Question 5

From what class of drugs does ivermectin belong?

Answer 5

Avermectin

Question 6

What route(s) can ivermectin be administered

Answer 6

PO, SC, topical

Question 7

Bennett et al. Multidimensional Cost-Benefit Analysis to Guide Evidence-Based Environmental Enrichment.1. How can bedding promote species specific behavior in NHPs?

Answer 7

Bedding helps promote foraging and provides a natural substrate for animals than bare pens provide. Also, reduces aggression, over grooming, and other abnormal behaviors.

Question 8

2. What are the major cost categories that should be considered when conducting a cost benefit analysis of environmental enrichment programs?

Answer 8

Cost categories should include: labor, materials, supplies and facilities maintenance costs.

Question 9

Pavek et al. Operation of an Air Filtration Device Results in Morbidity and Mortality in Growing Chickens (Gallus gallus domesticus
Oxidative damage has been found to result from ____________ exposure to sound levels __________ in numerous species.
A. Acute, 45-85dB
B. Chronic , greater than 85dB
C. Chronic, 45-85 dB
D. None of the above

Answer 9

B. Chronic and greater than 85db

Question 10

The hearing frequency range of chickens is:
A.  	4-16Hz
B.  	1-5 kHz
C.  	1-70kHz
D. 	0.35-3.15kHz

Answer 10

D. 0.35-3.15 kHz

Question 11

Macrovibration aversion and physiologic effects have been shown to occur in fully grown chickens. True or False

Answer 11

True

Question 12

Arbona et al. Treatment and Eradication of Murine Fur Mites.1. Which species of fur mites is reported to preferentially inhabit the forehead and cheeks?

Answer 12

Myobia musculi

Question 13

2. Which species reportedly prefers the ventral abdomen and inguinal areas?

Answer 13

Mycoptes musculinus

Question 14

3. In this study, what percentage of animals tested positive with the pelt examination?

Answer 14

Zero

Question 15

4. True or False: these authors implemented a 3 month post treatment testing moratorium prior to initiating follow up testing.

Answer 15

True

Question 16

Tavakkol et al. Resident Bacteria Flora in the Skin of C57BL/6 Mice .Which bacterial genus was the most commonly cultured from the mice SPF C57BL/6 used in this study?

a. Staphylococcus
b. Enterococcus
c. Bacillus
d. Streptococcus

Answer 16

a. Staphyococcus

Question 17

T/F: Culture techniques alone are sufficient for quantifying and identifying the microflora from skin samples.

Answer 17

False

Question 18

Which of the following Staphylococcus species was not isolated from the mice in this study?

Answer 18

S. epidermis–the comst predominant on human skin.

Question 19

Reynolds et al. Noise in a Laboratory Animal Facility .How is it that the noise of a jack hammer, which produces noise of a high decibel level, can be heard by humans but not mice?

Answer 19

Jackhammers prodcue noise of a high decible level but a low frequency; this frequency is low enough and out of the range where a mouse cannot accurately hear it.

Question 20

What is the hearing range of a mouse in frequency?

Answer 20

Ultrasonic, 1-100KHz

Question 21

What are the OSHA limits for decibel exposure for an employee without hearing protection averaged over an 8 hour work day?

Answer 21

90 Db

Question 22

What is the limit of decibel exposure over an 8 hour work day that then requires annual testing/training

Answer 22

85 dB

Question 23

Kanthaswamy et al. Population Genetic Statistics from Rhesus Macaques .List ways in which animal populations lose genetic diversity

Answer 23

Founder effect, intergenerational drift, nonrandom mating, genetic bottlenecks

Question 24

T/F – Macaques of full-Chinese, full-Indian, or hybrid origin may be used interchangeably in all research studies.

Answer 24

False.Macaques of full-Chinese and full-Indian origins can exhibit profound phenotypic differences in physiologic and behavioral traits that are controlled by genetic mechanisms. Inclusion of macaques from different geographic regions or their hybrids in experimental research may confound interpretation of phenotypic differences due to inflation of the genetic contribution to phenotypic variances.

Question 25

Adamson et al. Assessment of Carprofen and Buprenorphine on Recovery of Mice .What were the factors used to assess the pain score in the mice, and what postural movement indicative of pain was noted in all post surgical groups?

Answer 25

Hair coat, eyes, coordination and posture and overall condition were assessed in the scoring system. The abdominal stretch, and stretch and walk, were commonly noted in all post surgical groups.

Question 26

What treatment appeared to have the most negative effect on post operative recovery? a. Saline b. Buprenorphine c. Carprofen d. Combination of buprenorphine and carprofen

Answer 26

B. Buprenorphine

Question 27

What important conclusions were made by the researchers regarding pain management in laboratory animals?

Answer 27

Analgesic choice and the level of pain must be considered to help eliminate negative consequences on post operative recovery. Visual assessments of pain should be used carefully as some analgesics may have side effects that elevate the score. There is a need for further exploration of pain management dosing regimens and drugs in laboratory species.

Question 28

Bourque et al. Comparison of Buprenorphine and Meloxicam for Postsurgical Analgesia in Rats.Which of the following is not an adverse effect reported with use of buprenorphine in rodents? a. Rebound hyperalgesia b. Variability in potency between sexes c. Variability in potency between strains d. Anorexia and/or pica e. Renal toxicity

Answer 28

e. Renal toxicity

Question 29

Which of the following statements is not supported in this study comparing post-operative use of buprenorphine and meloxicam in rats? a. Meloxicam causes less reduction in body weight than buprenorphine b. Meloxicam causes less reduction in food consumption than buprenorphine c. Meloxicam causes less reduction in locomotor activity than buprenorphine d. Meloxicam has less stimulatory effect on daytime heart rate measurements than buprenorphine e. Meloxicam has less stimulatory effect on nighttime mean arterial pressure than buprenorphine

Answer 29

d. Melsoxicam has less stimulatory effect on daytime heart rate measurements than buprenorphine.

Question 30

Roble et al. A Comprehensive Laboratory Animal Facility Pandemic ResponseWhy is cryopreservation recommended in the article?

Answer 30

To mitigate research losses in the event of large scale animal euthanasia

Question 31

Which of the following is NOT a major consideration when creating a pandemic response plan? a. Recruitment of essential personnel b. Food and bedding supplies c. Animal euthanasia d. Large scale utility outages e. Disposal of animal carcasses

Answer 31

Large scale utility outages

Question 32

T/F. During an influenza outbreak, there is a potential for humans to pass the virus to animals in the research facility.

Answer 32

True

Question 33

Arbona et al. Treatment and Eradication of Murine Fur Mites.1. True/False Ivermectin administration has been associated with toxicity in some mouse strains and stocks

Answer 33

True

Question 34

2. How long is the life cycle for Myobia musculi and Mycoptes musculinus

Answer 34

Myobia musculi = 23 days | Mycoptes musculinus = 8-14 days

Question 35

3. True/False Chronic ascariasis may provoke secondary amyloidosis due to long-standing dermatitis.

Answer 35

True

Question 36

Schutt and Turner. Microchip-Associated Sarcoma in a Shrew, What is the genus and species of the house musk shrew? a. Suncus murinus b. Mus musculus c. Rousettus aegyptiacus d. Octogon degus e. Acrobates pygmaeus

Answer 36

a. Suncus murinus = shrew

Question 37

Microchip-associated neoplasms of laboratory animals are generally classified as: a. Neuroendocrine and malignant b. Epithelial and benign c. Neuromuscular and benign d. Mesenchymal and malignant e. Round-cell and malignant

Answer 37

Mesenchymal and malignant

Question 38

Vimentin is an immunohistochemical marker for which type of tissue? a. Neural b. Endocrine c. Mesenchymal d. Smooth muscle e. Adipose

Answer 38

c. Mesenchymal

Question 39

Hamir and Rupprecht. Pulmonary Idiopathic Alveolar Ossification in a Raccoon .Name the genus and species of the common raccoon

Answer 39

Procyon lotor

Question 40

What is a common histochemical stain for amyloid?

Answer 40

Congo Red

Question 41

What modified histochemical stain was used in this study to identify intracytoplasmic and intranuclear lead inclusions?

Answer 41

Ziehl-Neelsen

Question 42

Asfaw and Sun. Presumed Mycobacteriosis in Laboratory Zebra Finch .1. Which form of presumed mycobacteriosis was found in the duodenum of the Zebra finch?

Answer 42

Atypical form

Question 43

2. Which of the following is the scientific name of the Zebra finch? a. Spinus cucullatus b. Carduelis carduelis c. Taeniopygia guttata

Answer 43

C. Taeniopygia guttata

Question 44

3. Which stain was used to identify the organisms presumed to be Mycobacterium spp?

Answer 44

Acid-Fast (Ziehl-Neelsen)

Question 45

Daviau and Merton. Nonsurgical Repair of a Pseudoaneurysm in a Cynomolgus Macaque .1. Pseudoaneurysm and formation of AV fistulas are common complications of femoral blood draws in NHP. T/F

Answer 45

False. These are rare.

Question 46

2. What feature can be palpated to differentiate between a hematoma and pseudoaneurysm?

Answer 46

Hematomas are static whereas a trill can be palpated in a pseudoaneurysm as the blood flows with the cardiac cycle.

Question 47

3. UGCR requires: a) an ultrasound probe b) a stent c) surgical access of the pseudoaneurysm d) Doppler verification of the absence of an AV fistula

Answer 47

a. ultrasound probe.