Flashcards in Lecture 36: Psychoneuroimmunology Deck (5)
***What did Ader & Cohen’s 1975 study tell us about the body’s immune responses?
ran antibody. they found that the mice had the Sac and CY unpaired then thay have a normal antibody response
when Sac, but never experienced CY, there was no difference, it was normal
water - no difference, normal, but when injected with Sac - massive suppression of immune activity
Sac = Saccharin; CY = cyclophosphamide
***What are the 3 main ways that the brain can tune the immune response?
1. neuroendrocrine regulation (stress axis)
2. pautonomicnervous activity: sympathetic and parasympathetic
3. neurogenic inflammation from peripheral nerves
***What are sickness behaviours?
are caused by the production of inflammatory cytokines in the brain in areas important for: stess response, motivation, and cognition
***What causes sickness behaviours?