MOD 3 - COURSE 1 - PT 5 - lymphatic system Flashcards
what is the lymphatic system
- circulatory system - carry lymph directionally towards the heart
- filter mechanism - defence against pathogens
where does the lymph fluid flow
- travels from intrercellular spaces by way of lymph vessels - fluid moves towards the heart passing through many lymph nodes along the way
where is the fluid filtered to remove dead cells, bacteria and foreign material
lymph nodes
where is the cleaned fluid returned too
returned to hear via lymph vessels - becomes part of the plasma
how can you divide the lymphatic system
- conducting system
- lymphoid tissue
- lymph
what is the lymphatic conducting system
- carries lymph and consists of tubular vessles (cappilaries and vessels)
where does the conducting system originate from
intracellular spaces as lymphatic capillaries
where does the lymph go after the lymphatic capillaries
these merge into larger lymphatic vessel which merge into main lympahtic ducts - along whcih there are numerous lumph nodes
these ducts empty into venous system - where evnous cava enters heart
what is the lymphoid tissue
- immunce functions - pathogens and tumour spread
- consids of connective tissuewith various WBC embedded in it - most numerous = lymphocytes
what catagpries of lymphoid tissues are?
- primary lympphoid organs
- secondary lymphoid organs
what is the primary lymphoid organ?
- differentiation, proliferation and maturation of stem cells - into immuno cells occur
- thymus (T cell maturation) and bone marrow constitute primary lymphoid tissue
(production and early selectivity of lymphocytes)
what is secondary (peripheral) lymphoid organs?
maintain mature naive lymphoid tissues and initiate adaptive immune response
- provide enduronemen for anltered native molecules - to interact with lymphocytes (i.e. antigens
i.e. lymph nodes, spleen, MALT
what are lymph nodes
- reposnible for filtering out microbes, for acquired immune response against antigens
what are teh 2 differentiated zones of lymph nodes
= cortex - rich in B cells (follicles) - which are in contact with T cells - necessary for antibody production
= medulla - activated B cell - mature into plasma cells - decretate large amounts of antibodies
what is MALT
- Mucosa associated lymphoid tissue
- collection of lymphoid tissue that line the resp, gut & genitourinary tracts
- produce immune response against pathogens - invade mucosa
what is lymph fluid / how is it formed
recycled blood plasma
- blood doesnt come in direct contact with parenchymal cells and tissue in the body but constituents of blood exits microvascular exchnage vessels becoming interstitial fluid - comes into contact with parenchymal cells of body
- this intersitital fluid enters lymph vessels - and returns to heart like rest of blood
