MOD 3 - COURSE 6 - PT 4

Question 1

WHAT IS THE USE OF FASTINg?

Answer 1

• restrict feeding schedules - common in pharmacological research - standardize experiemnts - increase bioadvailability - and absorption of durgs may affect welfare

Question 2

under ad libtum - when do noctornal aniamls eat

Answer 2

• night cycles - few in the day

Question 3

if you were to remove food of nocturnal aniamls in dark cycles - whatr would happen

Answer 3

• difference in physiology, neurochemcistry and behaviour - alter pharacological agents

Question 4

whats the effects of fasting

Answer 4

• cause stress
  agression
  reduction in body weight
  body temp
  plsma glucose level
  reduce basal metabolic rate
• may need individual house which also isnt goof

Question 5

when can fasting be used

Answer 5

• only when scientifically justified

Question 6

how long should fasting tak place for?

Answer 6

THIS IS IMPORTANT - WANT TO LIMIT FASTING TIME AS MUCH AS POSSIBLE
- stomach of rat = empty after 6 hours of initiationof fasting
- no signif difference between 6 hours and 18 hours - rates and mice - but rats an dmice - intestinal tract = not completely emptyy

Question 7

why shoudl sudden fasting be avoided

Answer 7

• gradual adaptation to periods with restricted food = causes less stress same results