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Flashcards in Pulm Deck (30)
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1
Q

V/Q Ratio of APEX at rest

A

3

2
Q

V/Q Ratio of BASE at rest

A

0.6

3
Q

V/Q Ratio of APEX at exercise

A

1 (vasodilation of apical capillaries)

4
Q

V/Q Ratio of 0

A

SHUNT (airway obstructed, so 100% O2 will not help)

5
Q

V/Q Ratio of infinity

A

PHYSIOLOGIC DEAD SPACE (blood flow obstruction, so 100% O2 will help)

6
Q

Pressures at APEX

A

PA > Pa > Pv

7
Q

Pressures at middle lung

A

Pa > PA > Pv

8
Q

Pressures at BASE

A

Pa > Pv > PA

9
Q

Where is CO2 bound on carbaminohemoglobin?

A

N-terminus of globin

10
Q

What part of the lung does asbestosis affect?

A

lower lobes

11
Q

What part of the lung do silica and coal affect?

A

upper lobes

12
Q

What is anthracosis?

A

asymptomatic condition of urban dwellers exposed to sooty air

13
Q

What does silicosis increase risk for?

A
  • Tb (disrupts phagolysosomes and macrophages)

- Branchogenic carcinoma

14
Q

Lung cancer that cavitates

A

squamous cell carcinoma

15
Q

Lung cancer that is most common in non-smokers (and overall)

A

adenocarcinoma

16
Q

Central lung cancers

A

Squamous cell carcinoma

Small cell carcinoma

17
Q

Lung cancer with hypercalcemia

A

Squamous cell carcinoma (produces PTHrP)

18
Q

Lung cacner with k-ras, EGFR, or ALK mutations

A

Adenocarcinoma

19
Q

Peripheral lung cancers

A

Adenocarcinoma

Large cell carcinoma

20
Q

Inoperable lung cancer

A

small cell carcinoma

21
Q

Chromogranin A + lung cancer

A

Bronchial carcinoid tumor

22
Q

Lung cancer that secretes ACTH or ADH

A

small cell carcinoma

23
Q

Lung cancer that grows along alveolar septa

A

Bronchioloalveloar subtype of adenocarcioma

24
Q

Lung cancer that leads to Lambert-Eaaten syndrome

A

Small cell carcinoma

25
Q

Lung cancer that is associated with amplification of myc oncogenes

A

Small cell carcinoma

26
Q

Lung cancer with neuroendocrine Kulchitsky cells (small dark blue cells)

A

Small cell carcinoma

27
Q

Lobar pneumonia bugs

A

S. pneumoniae

Legionella or Klebsiella

28
Q

Bronchopneumonia bugs

A

S. pneumoniae
S. aureus
H. flu
Klebsiella

29
Q

Interstitial (atypical) pneumonia bugs

A

Viruses (flu, RSV, adenovirus)
Mycoplasma
Legionella
Chlamydia

30
Q

Lung abscess bugs

A

S. aureus
Bacteroides
Fusobacterium
Peptostreptococcus