What is Synaptic Transmission
process by which one neuron communicates with another
Step 1 Synaptic Transmission
-Action Potential arrives at pre-synaptic cleft in form of electrical signal
Step 2 Synaptic Transmission
-Vesicles bind with membrane of presynaptic button
Step 3 Synaptic Transmission
-Neurotransmitters are released where they can diffuse across the synaptic gap
Step 4 Synaptic Transmission
-Neurotransmitters bind with their specific receptors found on the outer membrane of post synaptic button
Step 5 Synaptic Transmission IF EXCITATORY
-If neurotransmitter is excitatory and enough neurotransmitters bind with receptors, action potential will be fired
Step 5 Synaptic Transmission IF INHIBITORY
-If neurotransmitters inhibitory and enough neurotransmitters bind with receptors action potential will be prevented from firing
Step 6 Synaptic Transmission
-Neurotransmitters ‚recycled’ by re-entering presynaptic button via re-uptake ports so that process can start again
Define neurotransmitter
-chemical messenger that carries, boosts and modulates signals between neurons and other cells
Excitatory Neurotransmitters
-have excitatory effects on neuron
-increase likelihood that neuron will fire action potential
-help attention and alertness
-triggered by daylight
Inhibitory Neurotransmitters
-inhibitory effects on neuron
-decrease likelihood that neuron will fire action potential
-slow down neural activity
-triggered as light levels reduced
Effects of drugs on synapse
-mimic neurotransmitters
-remain bound with receptor
-block neurotransmitters from reuptake
Effect of drugs mimicking neurotransmitters
-increase level of neurotransmitter in synapse
Effect of drugs remaining bound with receptors
-increase number of neurotransmitters tbat bind with receptors
Effect of drugs blocking neurotransmitters from reuptake
-block from entering reuptake valve
-neurotransmitters remain in synapse for longer, prolonging effects