tues 25 Flashcards
(34 cards)
name the 2nd gen antipsychotics?
Olanzapine, Quetiapine, Aripiprazole, Ziprasidone, Risperidone, Clozapine
2nd gen antipsychotics are better at treating what than the 1st gen?
the negative symptoms of schizophreni
2nd gen antipsychotics are more likely to cause which side effects?
Metabolic - dyslipidemias, weight gain, metabolic syndromes, etc.
2nd gen antipsychotics are less likely to cause which side effects?
the antimuscarinic side effects
which 2nd gen antipsychotic is associated with myocarditis and cardiomyopathy?
clonazapine
name the low potency first gen antipsychotics?
chlorpromazine, thioridazine
which side effects are more likely to be caused by low potency than high potency FIRST gen antipsychotics?
- antimuscarinic
- orthostatic hypotensino
- anti-histamine effects
which side effects are more likely to be caused by HIGH potency than LOW potency FIRST gen antipsychotics?
the extrapyramidal side effects, galactorea and impotence and neuroleptic malignant sydrome
which disease is associated with increased PATERNAL age of the FATHER?
achondroplasia
what is the trinucleotide repeat seen in myotonic dystrophy?
CTG
HLAB27 =
ankylosing spondylitis
HLAB8 =
graves disease
HLA B51 =
behcet syndrome
what is behcet syndrome?
disease characterize by blood vessels inflammation
presentation of behcet syndrome?
- arhtritis
- enthesitis
- vasculitis throughout body
- skin lesinos
pathophys of achondroplasia?
constituitively active FGF 23 impairs chondrocyte proliferation and differentation
HLADQ1 =
pemphigus vulgaris
HLA DR3 =
graves
HLA DR5 =
hashimotos
antidote to iron toxicity?
deferoxamine
antidote for lead toxicity?
succimer
flattened t waves =
hypokalemia
peaked t waves=
hyperkalemia
which disease has rosenthal fibers?
pilocytic astrocytoma
