Unit 1: Neurotransmitters and Receptors Flashcards Preview

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Flashcards in Unit 1: Neurotransmitters and Receptors Deck (76)
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1

L1: _____ ACh receptors have ionotropic actions.

Nicotinic

2

L1: _____ ACh receptors have metabotropic actions.

Muscarinic

3

L1: Acetylcholine is produced from a reaction between _____ and ______.

Acetyl-CoA and choline

4

L1: ACh is taken up into vesicles by ______.

Vesical Associated Transporter (VAT)

5

L1: ACh receptors can be divided into the _____ and ______ categories.

Muscarinic, Nicotinic

6

L1: ACh signals are terminated by _____.

Enzymatic degradation by ACh esterase

7

L1: Epinephrine-binding receptors include ______.

alpha-1, alpha-2, beta-1, and beta-2 adrenergic receptors

8

L1: GABA receptors include ______.

GABA-A and GABA-B

9

L1: GABA signals are terminated by ______.

reuptake

10

L1: Glutamate is converted to _____ by astrocytes.

Glutamine

11

L1: Glutamate signals are terminated by _____.

reuptake

12

L1: Monoamine signals are terminated by ______.

reuptake

13

L1: Monoamines are taken up into vescles by ______.

Vesicular Monoamine Transporter (VMAT)

14

L1: Monoamines may be degraded in nerve terminals by ______.

Monoamine Oxidase (MAO)

15

L1: Norepinephrine-binding receptors include ______.

alpha-1, alpha-2, and Beta-1 adrenergic receptors

16

L1: The most important indoleamine transmitter is ______.

5-HT (Serotonin)

17

L1: The three most important catecholamines are ______. (3)

Dopamine, EPI, NOR

18

L1: Which G protein pathway decreases intracellular concentrations of cAMP?

G-i/o

19

L1: Which G protein pathway depresses adnylyl cyclase (AC)?

G-i/o

20

L1: Which G protein pathway increases intracellular concentrations of cAMP?

G-s

21

L1: Which G protein pathway increases intracellular concentrations of DAG and IP3?

G-q

22

L1: Which G protein pathway stimulates adenylyl cyclase (AC)?

G-s

23

L1: Which G protein pathway stimulates phospholipase C (PLC)?

G-q

24

L1: Which neurotransmitters participate in diffuse systems?

ACh and Monoamines

25

L1: Which neurotransmitters participate in hierarchical systems?

Glutamate and GABA

26

L2: ACh production is catalyzed by ______

Choline Acetyl Transferase (CAT)

27

L2: ACh receptors include ______.

N-N, M1-M4

28

L2: AMPA receptors increase ____ ion influx

Calcium and Sodium

29

L2: GABA is produced from ______

Glutamate

30

L2: GABA synthesis is catalyzed by ________.

Glutamic Acid Decarboxylase