Flashcards in Unit 1: Neurotransmitters and Receptors Deck (76)
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1
L1: _____ ACh receptors have ionotropic actions.
Nicotinic
2
L1: _____ ACh receptors have metabotropic actions.
Muscarinic
3
L1: Acetylcholine is produced from a reaction between _____ and ______.
Acetyl-CoA and choline
4
L1: ACh is taken up into vesicles by ______.
Vesical Associated Transporter (VAT)
5
L1: ACh receptors can be divided into the _____ and ______ categories.
Muscarinic, Nicotinic
6
L1: ACh signals are terminated by _____.
Enzymatic degradation by ACh esterase
7
L1: Epinephrine-binding receptors include ______.
alpha-1, alpha-2, beta-1, and beta-2 adrenergic receptors
8
L1: GABA receptors include ______.
GABA-A and GABA-B
9
L1: GABA signals are terminated by ______.
reuptake
10
L1: Glutamate is converted to _____ by astrocytes.
Glutamine
11
L1: Glutamate signals are terminated by _____.
reuptake
12
L1: Monoamine signals are terminated by ______.
reuptake
13
L1: Monoamines are taken up into vescles by ______.
Vesicular Monoamine Transporter (VMAT)
14
L1: Monoamines may be degraded in nerve terminals by ______.
Monoamine Oxidase (MAO)
15
L1: Norepinephrine-binding receptors include ______.
alpha-1, alpha-2, and Beta-1 adrenergic receptors
16
L1: The most important indoleamine transmitter is ______.
5-HT (Serotonin)
17
L1: The three most important catecholamines are ______. (3)
Dopamine, EPI, NOR
18
L1: Which G protein pathway decreases intracellular concentrations of cAMP?
G-i/o
19
L1: Which G protein pathway depresses adnylyl cyclase (AC)?
G-i/o
20
L1: Which G protein pathway increases intracellular concentrations of cAMP?
G-s
21
L1: Which G protein pathway increases intracellular concentrations of DAG and IP3?
G-q
22
L1: Which G protein pathway stimulates adenylyl cyclase (AC)?
G-s
23
L1: Which G protein pathway stimulates phospholipase C (PLC)?
G-q
24
L1: Which neurotransmitters participate in diffuse systems?
ACh and Monoamines
25
L1: Which neurotransmitters participate in hierarchical systems?
Glutamate and GABA
26
L2: ACh production is catalyzed by ______
Choline Acetyl Transferase (CAT)
27
L2: ACh receptors include ______.
N-N, M1-M4
28
L2: AMPA receptors increase ____ ion influx
Calcium and Sodium
29
L2: GABA is produced from ______
Glutamate
30
