Unit 2: CNS Tumors Flashcards Preview

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Flashcards in Unit 2: CNS Tumors Deck (35):
1

L1: What Tumor Grade? Anaplastic Astrocytoma

III

2

L1: What Tumor Grade? Anaplastic Ependymoma

III

3

L1: What Tumor Grade? Anaplastic Oligodendroglioma

III

4

L1: What Tumor Grade? Choroid Plexus Papilloma

I

5

L1: What Tumor Grade? Diffuse Astrocytoma

II

6

L1: What Tumor Grade? Ependymoma

II

7

L1: What Tumor Grade? Ganglioma

I

8

L1: What Tumor Grade? Glioblastoma

IV

9

L1: What Tumor Grade? Medulloblastoma

IV

10

L1: What Tumor Grade? Meningioma

Usually I

11

L1: What Tumor Grade? Oligodendroglioma

II

12

L1: What Tumor Grade? Pilocytic Astrocytoma

I

13

L1: Which tumor frequently spreads through the CSF axis?

Medulloblastoma

14

L2: What genetic marker is commonly involved in medulloblastoma?

Shh

15

L2: What genetic marker is commonly involved in pilocytic astrocytoma?

B-Raf

16

L2: What histologic features in a glioblastoma are not typically seen in anaplastic astrocytoma?

Microvascular proliferation, necrosis

17

L2: What is the most common type of glioma?

Glioblastoma

18

L2: What is the typical age onset of diffuse astrocytoma?

3rd to 5th decades

19

L2: What is the typical age onset of ependymoma?

First two decades of life

20

L2: What is the typical age onset of Glioblastoma?

5th to 6th decades

21

L2: What is the typical age onset of medulloblastoma?

3-8 years

22

L2: What is the typical age onset of meningioma?

older adults

23

L2: What is the typical age onset of oligodrendroglioma?

Adulthood

24

L2: What is the typical age onset of pilocytic astrocytoma?

Childhood

25

L2: What is/are the most common anatomic site(s) for diffuse astrocytoma?

White matter of cerebral hemispheres

26

L2: What is/are the most common anatomic site(s) for ependymoma?

Fourth ventricle

27

L2: What is/are the most common anatomic site(s) for ganglioma?

Temporal lobe

28

L2: What is/are the most common anatomic site(s) for medulloblastoma?

Cerebellar vermis

29

L2: What is/are the most common anatomic site(s) for meningioma?

Adjacent to the dura

30

L2: What is/are the most common anatomic site(s) for oligodendroglioma?

Cerebral hemisphere white matter with penetration of overlying gray cortex

31

L2: Which tumor originates from external granule cell layers?

Medulloblastoma

32

L3: What genetic marker is commonly involved in diffuse astrocytoma?

IDH, TP53 mutation/17p loss

33

L3: What genetic marker is commonly involved in oligodendroglioma?

IDH, 1p/19q LOH

34

L3: What is/are the most common anatomic site(s) for choroid plexus papilloma?

lateral ventricles (children), fourth ventricle (adult)

35

L3: What is/are the most common anatomic site(s) for pilocytic astrocytoma?

Cerebellar hemispheres, optic nerves and chiasm, hypothalamic region