Unit 3: Cerebellum Flashcards Preview

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Flashcards in Unit 3: Cerebellum Deck (50):
1

L1: _____ fibers fire when the inferior olivary nucleus detects a discrepancy between planned and actual motor performance

Climbing

2

L1: _____ fibers originate in the _______ and contact only a about a dozen Purkinje fibers

Climbing; contralateral inferior olivary nucleus

3

L1: _____ fibers provide ______ input to granule cells.

Mossy; excitatory

4

L1: Anatomical location of corticocerebellum

lateral hemispheres

5

L1: Cell layer beneath the molecular layer and above the granule cell layer

Purkinje fiber layer

6

L1: Cerebellar fibers decussate _______ (rostral/caudal) to the cerebellum

Rostral

7

L1: Cerebellar lesions can result in ______ tremors.

Intention

8

L1: Cerebellar lesions result in ___-lateral deficits

ipsi-

9

L1: Climbing fiber input results in a _____ spike.

complex

10

L1: Dendrites of Purkinje fibers lie in the _____ layer.

molecular

11

L1: Each ______ cell is contacted by a single _____ fiber.

Purkinje; climbing

12

L1: Input and output of corticocerebellum

Cortical regions

13

L1: Mossy fiber input results in a _____ spike.

simple

14

L1: The ______ acts as a comparator for actual and expected movement

inferior olivary nucleus

15

L1: The major inputs to the cerebellum are carried in the ________.

Inferior and middle cerebellar peduncles

16

L1: The major outputs from the cerebellum are carried in the _______.

Superior cerebellar peduncle

17

L1: What term? Inability of a patient to bring a limb to the desired/required point in space

dysmetria

18

L1: What term? Inability of a patient to execute rapid alternating movements

dysdiadochokinesia

19

L1: What term? Loss of coordination or timing of muscles

ataxia

20

L1: Which anatomical region of the cerebellum does not synapse in the deep nuclei?

Flocculonodular lobe

21

L2: ______ have fibers that project to the ______ layer where the bifurcate into ______ fibers.

Granule cells; molecular; parallel

22

L2: ______: inhibitory interneurons scattered in the molecular layer

Basket and stellate cells

23

L2: _____-ergic neurons from the _______ supply input to the inferior olivary nucleus

GABA; deep cerebellar nuclei

24

L2: Anatomical location of spinocerebellum

Vermis and paravermal region

25

L2: Anatomical location of vestibulocerebellum

Flocculonodular lobe

26

L2: Basket cells and stellate cells supply _____ input to Purkinje fibers.

inhibitory

27

L2: Climbing fiber firing results in activation of Purkinje cells simultaneously with ______, resulting in ________.

Parallel fibers; Long-term depression

28

L2: Efferent connections: Lateral hemispheres > _____ nucleus > ______

Dentate; contralateral ventrolateral (VL) thalamus to cortex

29

L2: Efferent connections: Paravermal region > _____ nucleus > _________

Nucleus interpositus; contralateral red nucleus

30

L2: Firing of the ION climbing fibers occurs when the input from _______ and _______ neurons does not cancel out.

GABA-ergic deep cerebellar nuclei, afferent sensory

31

L2: Input and output of vestibulocerebellum

vestibular organs; vestibular nucleus

32

L2: Long Term Depression ______ Purkinje fiber response to parallel fiber synapses

decreases

33

L2: Mossy and climbing fibers supply _____ input to the deep cerebellar nuclei

excitatory

34

L2: Parallel fibers and climbing fibers supply _____ input to Purkinje cells

excitatory

35

L2: Purkinje fibers supply _____ input to the deep cerebellar nuclei

inhibitory

36

L2: The ______ conveys joint angle calculations to the premotor cortex where calculations between actual and desired location are made

parietal cortex

37

L2: The cerebellum can be described as _________ controller.

an adaptive feed-forward

38

L2: The deep nuclei receive excitatory input from _______ fibers.

mossy and climbing

39

L2: The only output from the cerebellar cortex is via ______ fibers, which supply _____ input to the deep nuclei

Purkinje; inhibitory

40

L2: The parietal cortex supplies ______ fibers that synapse on _______ fibers.

corticopontine; pontocerebellar mossy

41

L2: The vermal and paravermal regions receive input from the _______.

spinal cord

42

L2: Three functional regions of the crerebellum

Vestibulocerebellum, spinocerebellum, corticocerebellum

43

L3: Efferent connections: Vermal region > _____ nucleus > __________

fastigial; vestibular nucleus, pontine reticular formation

44

L3: Function of the corticocerebellum

Initiation, planning, timing

45

L3: Function of the paravermal spinocerebellum

Distal Motor control

46

L3: Function of the vermal spinocerebellum

Posture, locomotion, gaze (axial)

47

L3: Function of the vestibulocerebellum

Balance, eye movement

48

L3: HANDS Tremor

hypotonia, ataxia, nystagmus, dysarthria, stance/gait, intention tremor

49

L3: Information from the motor cortices synapses with __________ nuclei and then proceeds to the ______ of the cerebellum.

ipsilateral pontine nuclei; contralateral lateral hemispheres

50

L3: Input and output of spinocerebellum

spinal afferents; motor control nuclei