Defense & Barriers 2: Skin Diseases Flashcards
disease name
= disease definition
what species is this in?
what sequelae can occur?
calcinosis cutis
= when dermal collagen mineralizes due to HYPERADRENOCORTICISM or EXOGENOUS CORTICOSTEROIDS
ONLY OCCURS IN DOGS
mineralizations are treated like FOREIGN BODIES and can cause SECONDARY BACTERIAL INFECTIONS
disease name
what 4 things you see here?
how is it usually dispersed & what does that tell you?
acquired canine atopic dermatitis
what 4 things?
1. lichenification
2. hyperpigmentation
3. erythema
4. alopecia
usually VENTRALLY dispersed, indicates ALLERGIC REACTION from CONTACT rather than another route
disease name
pathogenesis?
what 3 clinical signs are most common?
epidermolytic hyperkeratosis
INHERITED MUTATION, disease occurs as a COMMON RESPONSE TO INJURY
3 clinical signs?
1. ichthyosis
2. hyperpigmentation
3. hyperkeratosis
disease name
pathogenesis?
clinical signs are due to the skin’s….
what clinical signs are caused?
predisposed to..
lamellar ichthyosis phenotype
pathogenesis?
from MUTATION in TRANSGLUTAMINASE-1 that then causes INABILITY TO FORM CORNIFIED ENVELOPE
clinical signs are due to the skin’s ABNORMAL RESPONSE TO INJURY
clinical signs?
1. HYPERKERATOSIS
2. EPIDERMAL HYPERPLASIA
predisposed to SECONDARY BACTERIAL INFECTIONS
disease name
= what it is
how does it cause alopecia?
2 main clinical signs?
ACQUIRED canine sebaceous gland adenitis
= occurs when dogs LOSE SEBACEOUS GLANDS, and as a result skin becomes HYPERKERATOTIC
alopecia?
excess keratin CLOGS UP HAIR FOLLICLES and causes HAIR SHAFTS TO FALL OUT
clinical signs?
1. skin becomes DRY and ITCHY
2. in CURLY-HAIRED DOGS, hair turns STRAIGHT
what’s wrong with the puppy on the left?
HYPERKERATOSIS, causes hair shafts to stand up
what 2 clinical signs are present?
what disease is it caused by?
clinical signs?
1. lichenification
2. crusts
caused by MALASSEZIA dermatitis
what disease is causing this?
MALASSEZIA DERMATITIS
acantholysis can be caused by WHAT 2 MAIN THINGS?
what one thing RARELY causes acantholysis?
EDEMA AND BACTERIAL INFECTION
RARELY, dermatophytosis
equine urticarial reaction can cause what disease process?
ACANTHOLYSIS
what disease is this?
what are the 3 clinical signs we can see here?
what 2 things are needed to prove that it’s this disease? why is it difficult?
pathophysiology?
= VASCULITIS
3 clinical signs?
1. edema
2. hemorrhagic skin
3. sometimes necrosis
2 things needed?
1. damage to INSIDE of vessel
2. presence of INFLAMMATORY INFILTRATES in vessel
–> DIFFICULT BC CAN BE A DIAGNOSIS OF EXCLUSION
pathophysiology?
entire vessel DIES and is REPLACED BY FIBRIN
what disease is this? what type of reaction?
this is caused by a medical treatment –> what is it?
3 terms to describe ear tips
= VASCULITIS caused by TYPE 3 HYPERSENSITIVITY REACTION
to RABIES VACCINE
ear tips?
1. ulcerated
2. dry
3. necrotic
what disease is this/pathophys?
pattern?
what 2 areas is this most likely to occur/why?
= EPIDERMOLYSIS BULLOSA, basement membrane zone is weakened so SKIN SLOUGHS OFF
SUBEPIDERMAL VESICULAR DERMATITIS PATTERN
most likely to occur in areas that receive THE MOST MECHANICAL TRAUMA, like PAWS AND MOUTH
just ID this disease & pattern
EPIDERMOLYSIS BULLOSA
SUBEPIDERMAL VESICULAR DERMATITIS PATTERN
what disease does hyperplastic superficial perivascular dermatitis rule out? why?
PEMPHIGUS FOLIACEUS because it has an INTRAEPIDERMAL PUSTULAR dermatitis pattern
what is this disease?
“common name?”
what kind of condition is this?
what does it cause?
= JUVENILE CELLULITIS or “PUPPY STRANGLES”
STERILE condition that causes PYOGRANULOMATOUS INFLAMMATION
ID this disease process
**HOW DO WE KNOW?
= PANNICULITIS, TARGETS PANNICULAR ADIPOSE TISSUE so we see FAT CELLS
ID this disease process
= PANNICULITIS
what disease causes this? what is it?
= HYPERADRENOCORTICISM (Cushing’s)
skin is ATROPHIED and ends up SO THIN that WE CAN SEE VESSELS
what disease is this? what is it?
(hint = what are the big circular things?)
= HYPERADRENOCORTICISM causing EPIDERMAL ATROPHY & ATROPHY of SEBACEOUS GLANDS
