Membrane Potentials - resting Flashcards

1
Q

What are the 3 types of membrane potentials?

A

action potentials

graded potentials

resting membrane potential

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2
Q

what is the intracellular resting membrane potential?

A

-70mV

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3
Q

What way does the Na/K pump move sodium and potassium?

A

2 potassium into cell and 3 sodium out of the cell

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4
Q

What potassium channels are open at rest?

A

leaky K+ channels

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5
Q

When K+ move out of the cell through leaky channels, what happens to the intracellular charge?

A

becomes negative

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6
Q

What typeof gradient is created when K+ leaks out of the cell?

A

electrical gradient

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7
Q

What is it called when K+ leaks out through its leaky channels?

A

down its concentration gradient

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8
Q

When is equilibrium created of K+ leaking out of the cell?

A

when the electrical gradient is equal and opposite to the concentration gradient

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9
Q

When is the resting potential achieved?

A

when an equilibrium is reached between the electrical gradient and opposite to the concentration gradient

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10
Q

What is the resting membrane potential dependent on?

A

the concentration gradient

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11
Q

What is the equilibrium potential equation?

A
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12
Q

Why is the resting membrane potential different to -90mv? (neurones)

A

Cl-
Na2+
k+

not just postassium

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13
Q

What hasa high concentration inside the cell?

A

potassium

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14
Q

What has a high concentration outside the cell?

A

sodium and potassium

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15
Q

What way do leaky sodium and chloride channels?

A

move inside the cell

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16
Q

What is the equation for the membrane potential?

A
17
Q

What is P in the GHK equation?

A

relative probability, highest for potassium

18
Q

How much of the charge does the Na/K pump contribute o the resting membrane potential?

A

5mV

relies upon the leaky K channels

19
Q

Why does a high potassium diet not result in seizures?

A

blood brain barrier

capillaries sin the brain are especially tight

K+ cannot path through endothelial cells

protects the brain from changes in plasma

20
Q

Is the heart protected against K+ intake?

A

no