motor control - basal ganglia loop and cerebellum Flashcards

1
Q

Where does the major subcortical input to area 6 come from?

A

ventral lateral nucleus in dorsal thalamus

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2
Q

Where does most of your thought come down to?

A

basal ganglia / thalamus

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3
Q

Where does your thought go to in the thalamus?

A

ventrolateral nucleus of the thalamus

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4
Q

Where does the basal ganglia receive information from?

A

receives input from the frontal, prefrontal and parietal cortex

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5
Q

What do loop cycles allow?

A

you have a thought

send all the info you have to the basal ganglia

to the thalamus

and back up to the area 6

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6
Q

Describe the information loop?

A

an information loop cycles form cortex through thalamus and basal ganglia and back to SMA in cortex

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7
Q

where is the ventral lateral nucleus?

A

thalamus

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8
Q
A
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9
Q

Motor loop

A

A = frontal cortex neurone
B = putamen
C = globus pallidus
D = VL vetrolateral nucleus
E = SMA

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10
Q

Is the cortex to putamen excitatory or inhibitory?

A

excitatory

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11
Q

Is the putamen to globus pallidus excitatory or inhibitory?

A

inhibitory

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12
Q

Is the globus pallidus to VLo neurones excitatory or inhibitory?

A

inhibitory

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13
Q

Is the VLo to SMA ecitatory or inhibitory?

A

excitatory

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14
Q

How does the area 6 threshold get boosted beyond threshold for the ‘go’ signal?

A

when the SMA is boosted beyond a threshold level by activity coming through the basal ganglia funnel

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15
Q

Why are VL inhibited at rest?

A

the globus pallidus neurons are spontaneously active and inhibit VL

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16
Q

Describe the cortical excitation

A

cortical excitation

excited putamen which

inhibits globus pallidus which

releases cells in VLo from inhibition so

aciviy in VLo boosts SMA activity

17
Q

Is the basal ganglia loop positive or negative feedback?

A

positive feedback

18
Q

What houses around 50% of total brain neurones?

A

cerebellum

19
Q

What may lesions to the cerebellum cause?

A

ataxia: uncoordinated inaccurate movements

fail to touch nose with eyes shut

similar effects as alcohol

20
Q

What areas are a part of the huge cortico-ponto-cerebellar projection?

A

layer 5

areas 4 and 6 and somatosensory cortex

21
Q

What does the cortico-ponto-cerebellar projection connect?

A

cortex

pontine nuclei

cerebellum

22
Q

How does the cerebellum go back to the cortex?

A

ventrolateral thalamus (same as basal ganglia)

23
Q

What does the cortico-ponto-cerebellar projection allow?

A

allows cerebellum to instruct direction, timing and force movements