endocrinology 4 Flashcards

1
Q

Where is the adrenal gland?

A

fat layer on superior pole of the kidney

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2
Q

What is the adrenal gland composed of?

A

medulla and cortex

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3
Q

What is the embryological origin of the medulla?

A

neurohormonal origin

arises from neural crest tissue

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4
Q

Name a catecholamine?

A

adrenaline

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5
Q

What does the medulla of the kidney produce?

A

adrenaline - catecholamine

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6
Q

What is the true endocrine gland of the adrenal gland?

A

cortex

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7
Q

What is the neurohormonal component of the adrenal gland?

A

medulla

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8
Q

What is the embryological origin of the cortex?

A

mesodermal layer

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9
Q

What does the medulla of the adrenal gland produce?

A

produces steroid hormones

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10
Q

Name steroid hormones

A

cortisol

aldosterone

androgens

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11
Q

What component makes up 3/4 of the adrenal gland?

A

cortex

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12
Q

What is the function of the adrenal gland?

A
  • stress response
  • electrolyte balance
  • minor role in development of sexual characteristics
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13
Q

What hormones are responsible for the stress response?

A

cortisol (from cortex)

catecholamines (adrenaline) - from medulla

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14
Q

What hormone is responsible for the electrolytes balance?

A

aldosterone from cortex

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15
Q

What hormone is responsible for minor developmental or sexual characteristics?

A

androgens

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16
Q

How would you describe the adrenal medulla?

A

modified sympathetic ganglion

17
Q

What do the pre-ganglionic sympathetic fibres cause the adrenal medulla to release?

A

Ach

18
Q

What do the post-ganglionic cells lack?

what are these cells called?

A

axons/dendrites

called chromaffin cells

19
Q

What do chromaffin cells release?

A

adrenaline (and noradrenaline)

directly into bloodstream

20
Q

What is the effect of adrenaline released from the medulla?

A

rapid stress response

fight or flight

21
Q

Is the hypothalamus stimulating the adrenal gland rapid or slow?

A

rapid

22
Q

What are the physiological effects of adrenaline in the bloodstream?

A
23
Q

What can stimulate the hypothalamus to stimulate the medulla?

A

hypoglycaemia

exercise

stress