Blood 2; disorders and leukemia Flashcards
(122 cards)
1
Q
acquired neutropenia can come from
A
autoimmune issues
infection
induced from drugs
2
Q
malignant lymphomas
A
decrease immune response, solid tumor; asymmetrical painless node
3
Q
lack of rbc and platelets lead to
A
fatigue
random bruising
bleeding while brushing teeth from lack of platlets
4
Q
asymptomatic
more fully differentiated cells
insidious
A
chronic leukemias
5
Q
leading cause of death in children 1-14
A
acute leukemia
6
Q
abnormal B and T cells in lymphs
A
non-hodgkin lymphoma
7
Q
infectious mononucleosis is an example of a
A
lymphoproliferative disorder
8
Q
achy bones is a symptom of
A
white blood cell production
9
Q
necessary for transplants
A
agranulocytosis
10
Q
fever at night
A
tumor necrosis factor
11
Q
acute myelocytic leukemia info
A
affects 50 year olds but sometimes children
translocation of chromosome 15 to 17
more chromosome abnormalities are found in those with extra chromosomes (trisomy 21)
12
Q
IgM converts to
A
IgG in 2-3 months
13
Q
meaning gradual but with harmful affects
A
insidious
14
Q
wbc higher than 100K
A
leukocytosis
15
Q
also known as mono or kissing disease
A
infectious mononucleosis
16
Q
chronic leukemias traits
A
asymptomatic
more fully differentiated cells
insidious
17
Q
CML=
A
chronic myelogenous leukemia
18
Q
types of malignant lymphomas
A
non-hodgkin
hodgkin
19
Q
HL =
A
hodgkin reed sternberg cell
20
Q
non-hodgkin and hodgkin are types of
A
malignant lymphomas
21
Q
meaning the probable course of disease
A
prognosis
22
Q
mostly pre-b cell origin
A
acute lymphocytic leukemia
23
Q
epstein barr virus causes
A
infectious mononucleosis
24
Q
rapid increase in number
A
proliferation
25
majority survive more than ten years after diagnosis
chronic lymphocytic leukemia
26
reed sternberg cell is not found
non-hodgkin lymphoma
27
cachetin
weight loss from muscle wasting
28
EBV =
epstein barr virus
29
asymptomatic
symptoms
blasts
make up the
triphasil phases
30
chronic myelogenous leukemia traits
starts with BCR-ABL oncogene
triphasil - poor survival of less than 5 years
average is 67 years
stem cell transplant is only cure
31
affects 50 year olds but occassionally children
acute myelocytic leukemia
32
malignant neoplasm in blood forming organs; rapid proliferation of abnormal and immature wbc
acute leukemia
33
in white blood cell count increases, these decrease
red blood cells and platelets
34
acute means
fast acting
35
we have a fixed amount of
stem cells
36
IgM can be tested after
1 week
37
non-hodgkin lymphoma traits
```
rapid metastasis
reed sternberg cell not found
abnormal B and T cells in lymphs
H pylori infection in digestive tract
found in africa and japan
```
38
proliferation
rapid increase in number
39
triphasil phases
asymptomatic
symptoms
blasts
40
agranulocytosis is necessary for
transplants
41
traditional virus (days)
day 1 and 2 are fine
day 3 is ass (neutropenia)
day 4 is fine
42
leukopenia
abnormally low WBC
43
85% cure rate to kill cell
hodgkin reed sternberg cell
44
multiple myelomas
plasma cell dyscrasia
45
more chromosome abnormalities are found in
those with extra chromosomes (like trisomy 21)
46
epstein barr virus
hepatitis
hepatosplenomegaly
are all
infectious mononucleosis
47
decrease in red blood cell and platelets comes from an increase of
white blood cells
48
live 24 hours
white blood cells
49
neutropenia
reduced formation of stem cells
50
for NHL and HL, node swelling is
above the diaphragm
51
hepatosplenogaly info
enlargement of spleen and liver
running and jostling is no good
splenic rupture when enlarged kills in two hours
52
cancer moving from primary spot
metastasis
53
weight loss from muscle wasting
cachetin
54
for NHL and HL, pain starts
by stage 3 or 4
55
agranulocytosis
utmost lack of white blood cells
56
white blood cell lifespan
24 hours
57
H pylori infection in digestive tract
non-hodgkin lymphoma
58
fatigue
random bruising
bleeding while brushing teeth
lack of rbc and platelets
59
triphasil leads to
poor survival
60
causes most infectious mononucleosis
epstein barr virus
61
needs to be digested by liver to lower virus count
mono in epstein barr virus
62
tumor necrosis factor
fever at night
63
meaning shows no symptoms
asymptomatic
64
autoimmune issues
infection
or drugs can cause
acquired neutropenia
65
cancer of the plasma cells in older adults
multiple myelomas
66
leukocytosis
wbc higher than 100K
67
AML=
acute myelocytic leukemia
68
insidious
gradual but with harmful affects
69
infectious mononucelosis includes
epstein barr virus
hepatitis
hepatosplenomegaly
70
metastasis
cancer moving from primary spot
71
chronic lymphocytic leukemia
build up of b lymphocytes in bone marrow, lymph nodes, and blood
72
infectious mononucleosis is also known as
mono or kissing disease
73
found in africa and japan
non-hodgkin lymphoma
74
acquired means
from the first day of life
75
NHL =
non-hodgkin lymphoma
76
BCR-ABL oncogene starts
chronic myelogenous leukemia
77
enlargement of spleen and liver
hepatosplenomegaly
78
neoplastic disorders of hematopietic and lymphoid origin include
leukemias
malignant lymphomas
plasma cell dyscrasia
79
only known cure is stem cell transplant
chronic myelogenous leukemia
80
inflammation of the liver
hepatitis
81
results in the build up in B lymphocytes in bone marrow, lymph nodes and blood
chronic lymphocytic leukemia
82
messes up cardiovascular, liver, and spleen enlargement
mono in epstein barr virus
83
oncogene
beginning of a cancer cell
84
abnormally low WBC
leukopenia
85
acute leukemia definition
malignant neoplasm in blood forming organs, rapid proliferation of abnormal and immature wbc
86
hepatitis
inflammation of the liver
87
utmost lack of white blood cells
agranulocytosis
88
decrease immune response, solid tumor; asymmetrical painless node
malignant lymphomas
89
NHL has a higher death rate because
it mutates and is connected to bacterial and viral infections
90
chronic means
prolonged course
91
can be tested after 1 week
IgM
92
IgM converts to IgG in
2-3 months
93
B cell mutation in single lymphnode
hodgkin reed sternberg
94
hodgkins reed sternberg traits
b cell mutation in single node
85% cure rate to kill cell
15-40 years then after 55
95
ALL=
acute lymphocytic leukemia
96
meaning from the first day of life
acquired
97
HSM =
hepatoplenomegaly
98
chronic lymphocytic leukemia traits
diagnosed in 50-70 yo males
average of 72 years
majority survive more than ten years after diagnosis
99
symptoms include fatigue and mono within 3 weeks
epstein barr virus
100
reduced formation of stem cells
neutropenia
101
yellowing anywhere, especially the eyes, is a sign of
liver failure
102
symptoms include fatigue
| within 3 weeks feels like mono
epstein barr virus
103
multiple myeloma triats
```
after 60, average 71
bone pain is first symptom
insidious
poor prognosis
most people dont live past 3 years of diagnosis
```
104
asymptomatic
showing no symptoms
105
kinds of acute leukemia
acute lymphocytic leukemia
| acute myelocytic leukemia
106
example of lymphoproliferative disorder
infectious mononucleosis
107
acute lymphocytic leukemia info
affects 2-4 year olds
learns from abnormal DNA info
mostly pre-b cell origin
108
translocation of chromosome 15 to 17
acute myelocytic leukemia
109
acute leukemia info
keukocytosis
symptom of achy bones, fatigue, night sweats, weight loss, bleeding
exposure to radiation from powerlines at school may be related
leading cause of death in children 1-14
110
tell tale sign that something is wrong with the liver
yellowing anywhere, especially the eyes
111
number one symptom from white blood cell production
achy bones, legs an hips in particular
112
types of leukemias
acute and chronic
113
only known cure for chronic myelogenous leukemia
stem cell transplant
114
beginning of a cancer cell
oncogene
115
CLL
chronic lymphocytic leukemia
116
converts to IgG
IgM
117
epstein barr virus info
testing looks for antibodies instead of virus itself
symptoms include fatigue and mono within 3 weeks
mono messes up cardiovasular, liver, and spleen enlargement
mono needs to be digested by liver to lower count
118
starts chronic myelogenous leukemia
BCR-ABL oncogene
119
hepatosplenogaly
enlargement of spleen and liver
120
diagnosed in 50-70 yo males
chronic lymphocytic leukemia
121
affects 2-4 year olds
acute lymphocytic leukemia
122
prognosis
the probable course of disease
