Flashcards in DIT Antidotes Deck (23):
Ammonium Chloride to acidify urine to get rid of drug
benzo, antipsychotics, antihypertensives
N-acetylcystine (replenish glutathione)
NAPQI would kill hepatocytes, and glutathione will conjugate it to make not poisonous
Aspirin overdose antidote
Organophosphate OD tx?
pralidoxime (reactivate cholinesterase)
Beta blockers/Verapamil OD tx? (3 things)
Bradycardia: Glucagon (increases cAMP in myocardium)
Atropine takes away brakes
Calcium contractility increaed
Digitalis OD tx?
arrythmia is danger so you make sure potassium and magnesium are ok
If severe OD: Anti-Dig fragments
Supportive care usually works fine
Ate a bottle of vitamins, hematemesis, melana and lethargy tx?
Iron poisoning! (can happen with lots of transfusions)
DeFERoxamine, deFERasirox (easy to remember) which is chelating agent
Lead poisoning: child developmental delay, GI symptoms. How do you tx? 4 things
Mercury, arsenic or gold?
Think of dime for monetary unit for gold, or merca for mercury
Copper, arsenic or gold?
Penicillamine (copper pennies)
Cyanide toxicity (house fired, sodium nitroprusside)
Methemoglobin? blood is brown
Methylene blue, vit c
Carbon monoxide poisoning (lamps, heaters, stove...)
Methanol or ethylene glycol?
Alcohol is other option if not available
Flumazenil (remember Ben likes if fast? Flumazenil is Florence telling Ben no!)
Sodium bicarb (its acidic)
Protamine (H in heparin is like a proton, and Protamine is tx!)
Vitamin K (takes days)
FFP needed for acute Tx
tPA, streptokinase, urokinase tx?