Flashcards in Facility Design and Management Deck (78)
measures taken to detect, prevent, contain, and eradicate adventitious infections
define programming in terms of facility design
decision-making phase that defines the scope of the building project
what is in the program document in terms of facility design
describing in detail what research will be housed in the facility and its support requirements. ie space allocation summary, list of all square footage requirements
what are the pros and cons of a multi corridor system vs a single corridor system
multi cooridor system allows for better separation of clean and soiled materials but requires more space.
what are 4 types of animal housing areas?
conventional, quarantine, biocontainment, barrier
typical modular rodent room sizes
11ft x 22ft
what equipment should be fixed in an animal holding room?
sink, no casework, as open and flexible as possible
refers to facilities and management practices designes to isolate animals from infectious agents
levels of barrier
typically at the cage level. if using open top caging, may be at room level, isolators
standard rodent cage capacity of rooms
500-800 cages equates to 250-400 sq ft
most common cubicle size
4ft deep x 6 ft wide
benefits of cubicles
allows greater separation of animals by pecies, source, microbiological status, project, and experimental hazards.
air distribution in cubicle set up
asile is positive to cubicle. air from cubicle enters when door open and can then be forced into other cubicles when pressure is restored.
NHPs are housed under what biohazard status
special componenets of NHP housing
entry vestibule, lights and fixtures designed and secured so that animals free in the room cannot damage them, trough drain system, hose bibs
slope of floor for ideal drainage
3/16in per foot from crown to floor trough. slope in trough 1/4in per foot to drain
size of drain
4in minimum, should be 6in if will be washing down waste
ratio of support space to animal housing space
30:70 to 70:30
engineering features required when dealing with hazardous materials
physical isolation of animals and waste, room surfaces are monolithic, sealed, and easily sanitized, use of BSCs or chemical hood, increased room air exchange rates to dilute contaminants, directional airflow, room pressure differentials
chemical hoods provide protection for what? personnel, product, neither, both?
BSC Class II Type B2 provide protection for what? personnel, product, neither, both?
how long should caracaases and waste be allowed to decay before disposal into nonradioactive waste streams
10 half lives
removal of organic and nonorganic debris adhering to surfaces
reduces but does not eliminate microorganisms
combination of cleaning and disinfection
eliminates all life forms
preferred method of sanitiation of cages and equipment
mechanical washers and water at temps in excess of 180F
describe the set up of a constant volume reheat type of HVAC system
CVR system draws in 100% fresh air, then filter, heat or cool, and humidify before distributing it within the facility. Conditioned air delivered to individual rooms at a constant temperature and humidity is then reheated to the desired temperature at the room level based on settings of rooms thermostat
describe the set up of a variable air volume system?
ventilation rates can be tailored to maintain desired environmental conditions