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Flashcards in Facility Design and Management Deck (78)
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1

define biosecurity

measures taken to detect, prevent, contain, and eradicate adventitious infections

2

define programming in terms of facility design

decision-making phase that defines the scope of the building project

3

what is in the program document in terms of facility design

describing in detail what research will be housed in the facility and its support requirements. ie space allocation summary, list of all square footage requirements

4

what are the pros and cons of a multi corridor system vs a single corridor system

multi cooridor system allows for better separation of clean and soiled materials but requires more space.

5

what are 4 types of animal housing areas?

conventional, quarantine, biocontainment, barrier

6

typical modular rodent room sizes

11ft x 22ft

7

what equipment should be fixed in an animal holding room?

sink, no casework, as open and flexible as possible

8

define barrier

refers to facilities and management practices designes to isolate animals from infectious agents

9

levels of barrier

typically at the cage level. if using open top caging, may be at room level, isolators

10

standard rodent cage capacity of rooms

500-800 cages equates to 250-400 sq ft

11

most common cubicle size

4ft deep x 6 ft wide

12

benefits of cubicles

allows greater separation of animals by pecies, source, microbiological status, project, and experimental hazards.

13

air distribution in cubicle set up

asile is positive to cubicle. air from cubicle enters when door open and can then be forced into other cubicles when pressure is restored.

14

NHPs are housed under what biohazard status

ABSL2

15

special componenets of NHP housing

entry vestibule, lights and fixtures designed and secured so that animals free in the room cannot damage them, trough drain system, hose bibs

16

slope of floor for ideal drainage

3/16in per foot from crown to floor trough. slope in trough 1/4in per foot to drain

17

size of drain

4in minimum, should be 6in if will be washing down waste

18

ratio of support space to animal housing space

30:70 to 70:30

19

engineering features required when dealing with hazardous materials

physical isolation of animals and waste, room surfaces are monolithic, sealed, and easily sanitized, use of BSCs or chemical hood, increased room air exchange rates to dilute contaminants, directional airflow, room pressure differentials

20

chemical hoods provide protection for what? personnel, product, neither, both?

personnel only

21

BSC Class II Type B2 provide protection for what? personnel, product, neither, both?

both

22

how long should caracaases and waste be allowed to decay before disposal into nonradioactive waste streams

10 half lives

23

define cleaning

removal of organic and nonorganic debris adhering to surfaces

24

define disinfection

reduces but does not eliminate microorganisms

25

define Sanitation

combination of cleaning and disinfection

26

define sterilization

eliminates all life forms

27

preferred method of sanitiation of cages and equipment

mechanical washers and water at temps in excess of 180F

28

describe the set up of a constant volume reheat type of HVAC system

CVR system draws in 100% fresh air, then filter, heat or cool, and humidify before distributing it within the facility. Conditioned air delivered to individual rooms at a constant temperature and humidity is then reheated to the desired temperature at the room level based on settings of rooms thermostat

29

describe the set up of a variable air volume system?

ventilation rates can be tailored to maintain desired environmental conditions

30

final particulate filters found on most vivarium air handles filter what?

to 85-95% dust spot efficiency