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Flashcards in BB Ch 2 Deck (49)
1

AWA of 1966

licensing of dealers of dogs and cats. treatment before and after research

2

AWA of 1970

expanded to include regulated animals to include teaching, exhibition, wholesale pet industry, zoos. standards of care during research and includes more species

3

AWA of 1976

transportation guidelines

4

AWA of 1985

expanded to include IACUC, develop a national agriculture library, training of personnel

5

AWA of 1990

expanded to include holding period regulations

6

Fiscal year under AWA

Oct 1st to Sept 30

7

Annual report for AWA is due?

by Dec 1st

8

What should be in annual report to AWA/USDA

1. assure professionally acceptable standards were followed 2. each investigator considered alternatives

9

when can exceptions to standards of care be issued?

1. for health reasons. veterinarian can approve exemption that must be reviewed every 30 days unless it is a permenant condition

10

What type of information should the NAL provide

1) info pertaining to employee training

11

Who enforces AWA

USDA thru APHIS

12

definition of dealer

more that $500. buys sells or negotiates transport of animals for research

13

definition of animal

live or dead dog, cat, non-human primate, guinea pig, hamster, rabbit, aquatic mammal, or any other warm blooded animal that is used or is intended for use in research. Exludes: birds, Rattus, and Mus bred for use in research

14

composition of IACUC under AWA

3 members, one must be veterinarian and one non-affiliated members (no research personnel)

15

job of IACUC

conduct inspections of all animal study areas at least every 6 months, report should be signed by quorum and include minority views, file report with IO. deficiencies w/ timetable. program review q 6 months with minority views.

16

requirements of protocol review

1. identify species and number to be used

17

requirements for surgical procedures

1. use aseptic technique with sterile instruments

18

definition of adqueate veterinary care

availability of appropriate facilities, personnel, equipment, and services. appropriate methods to prevent, control, diagnose, and treat diseases and injuries and provide emergency veterinary care.

19

Pain category B

animals used for breeding, conditioning or being held

20

Pain category C

research will only include very brief pain or distress

21

Pain category D

appropriate anesthesia and analgesia is provided for distressful and painful procedures

22

Pain category E

Painful procedures are being performed w/o appropriate anesthesia or analgesia

23

law establishing the public health services policy

Health Research Extension Act 1985

24

The public health services policy is adminstered by:

OLAW under NIH under PHS

25

how often must the PHS assurance be refiled

typically 5 years but may be less depending on OLAW

26

PHS category 1

have AAALAC accredation

27

PHS category 2

do not have AAALAC accredation

28

definition of animal by PHS

all live vertebrate animals

29

in addition to PHS what does OLAW use for standards

Guide for the care and use of laboratory animals

30

composition of IACUC under PHS

5 members 1-veterinarian 2- non affiliated member 3- scientist 4 non-scientist

31

Function of IACUC under PHS

1. review institutional program q6 months

32

What should be involved in protocol review under PHS

1. avoid or minimize animal pain/discomfort

33

What should be included in the program description

1. list of every component of institution to be included

34

how long should records be kept under PHS and USDA

duration of activity plus three years

35

record keeping requirements of IACUC under PHS

1. copy of assurance

36

what needs to be in annual report to OLAW

any change in institutional category

37

US government principles for utilization and care of laboratory animals

1. transportation, care and use is in accordance with AWA

38

CIOMS

council for international organizations of medical sciences

39

differences between CIMOS and US principles

advancement and knowledge requires animal research

40

import and export regulations are overseen by

USDA APHIS for those animals that can carry diseases that infect livestock

41

CITES

convention of international trade in endangered species of wild fauna and flora

42

CITES in US is administered by

Department of Interior

43

CITES category I

endagered species

44

CITES category II

may become endangered if trade is not regulated

45

CITES category III

any species within a countries jurisdiction that they want to regulate

46

biohazadorous substances are regulated by

OSHA

47

chemical hazadorous substances are regulated by

OSHA, DEA, EPA

48

radioactive substances are regulated by

Nuclear Regulatory Commission (NRC)

49

regulations governing recombinant DNA

DHHS, NIH Guidelines for research involving recombinant DNA molecules. IBC institutional biosafety commission at institutions overseen by RO regulatory official/ biosafety officer