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Flashcards in Guinea pig Deck (125)
1

Guinea Pig

Cavia porcellus

2

models for


anaphylaxis



 


3

clasification of GP

hystricomorph

4

number of digits on fore and hind

four on the front and three on the back

5

ideal caging for GP

solid bottom cages with bedding

6

space requirement for GP up to 350g


60in^2


7

space requirement for GP >350g

101in^2

8

height requirement for GP cage

7in

9

ideal temp for GP


68-79F


10

predominant leukocyte in GP

lymphocyte

11

name of special leukocytes in peripheral blood

heterophil

12

where are Kurloff cells found most often and when?

in thymus, spleen, liver, lung during pregnancy

13

purpose of Kurloff cells

NK cell activity, cancer resistance?

14

which teeth are open rooted in the GP

all teeth (hyposodontic)

15

description of oral cavity in GP

small and narrow, soft palate coveres nearly the entire back of the pharynx, only small palatal ostium visible

16

Stomach of GP

monogastric hind gut fermentor, glandular epithelium all over

17

describe the Preyer or pinna reflex

cocking of the pinnae in response to a sharp sound.

18

what are the hormones responsible for growth regulation in GP

Insulin growth factor 1 & 2. (not pituitary growth hormone)

19

puberty

M: 3-4m

20

Gestation

59-72d

21

weaning age

14-28d

22

special requirement of GP feed

stabilized Vitamin C

23

how long can stabilized feed be stored

180d post milling

24

how long can unstabilized feed be stored

90d post milling

25

describe unique components of female reproductive tract

vaginal closure membrane

26

at what age does the pubic symphysis fuse?

6-9m

27

what hormone is responsible for relaxation of the pubic symphysis as parturition nears?

Relaxin

28

GP are ______ ovulators


spontaneous



nonseasonally polyestrous


29

postpartum estrus

highly fertile, 2-10h post delivery

30

placentation

labryinthine hemomonochorionic

31

description of Bordatella bronchiseptica

short gram neg rod, non spore forming

32

clinical signs of Bordatella bronchiseptica


subclinical infections most common but stress may predispose to outbreaks of sepsis resulting in acute death


33

reservoir of Bordatella bronchiseptica


respiratory tract of many species.



 



rabbits known to give to GP


34

necropsy findings of Bordatella bronchiseptica

pulmonary consolidation, exudate in upper and lower respiratory tract

35

tropism for Bordatella bronchiseptica

cilliated respiratory epitelium

36

description of Streptococcus equi subsp zooepidemicus

gram +, cocci chain, lancefield group C, B hemolytic, antiphagocytic capsule

37

clincial signs of Strep equ ssp zooepidemicus


abscess of cervical lymph nodes, abscess basically anywhere,



"thumps"



suppurative or caseous lymphadenitis, acute septicemia, otitis media, mastitis


38

transmission of Strep equi ssp zooepidemicus

via aerosol onto epithelium, zoonotic

39

most common types of Strep pneumoniae

types 4 and 19F

40

clincial signs of Strep pneumoniae


carrier state common



depression, anorexia, URI, torticolis, abortion, stillbirth



 


41

transmission of Strep pneumoniae

aerosol or direct contact with infected animals

42

necropsy findings of strep pneumoniae


pyogenic processes, fibrinopurulent pleuritis, pericarditis, suppurative pneumonia, otitis media, endometriosis, and arthritis


43

diagnosis of Strep pneumoniae

observe on gram stained impression smears, serotyping is necessary

44

treatment of Strep pneumoniae

BAD, more likely to cause a reversion to the subclinical state than eliminate infection

45

description of Salmonella

gram negative bacillus

46

most common serovars of Salmonella

enterica sub species enterica, serovars Typhimurium and Enteritidis

47

Clinical signs of Salmonella


peracute to acute: high morbidity and mortality rough hair coat, weakness, conjunctivitis, abortion, light colored feces, intermittent diarrhea



 



diarrhea rare in GP (common in rats)


48

transmission of Salmonella


can be shed by subclinical carriers, fecal-oral, blood-oral, tissue-oral, conjunctiva


49

gross lesions of Salmonella

hepatomegaly, splenomegaly, small yellow necrotic foci throught the viscera

50

diagnosis of Salmonella

recover organism, culture on MacConkey or brilliant green agar

51

treatment of Salmonella

BAD, may lead to subclinical infection

52

cause of Guinea Pig inclusion conjunctivitis

Chlamydia caviae

53

clinical signs of Chlamydia

reddening of eyelids, conjunctivitis, purulent exudate, self limiting with recovery in 3-4 weeks

54

diagnosis of Chlamydia

demonstration of intracytoplasmic inclusion bodies in Giemsa or Macchiavello stained conjunctival epithelial cells

55

clinical signs of Guinea Pig Adenovirus

subclinical most common, affected animals (stress or immunocompromised) die w/o prior signs

56

morbidity and mortality of adenovirus

low, high

57

necropsy of GP Adenovirus

dark red pulmonary consolidation, emphysema, catarrhal exudate, intranuclear inclusion bodies in respiratory epithelial cells

58

cytomegalovirus is what kind of virus?


caviid herpes virus 2, beta herpes virus


59

clincial signs of CMV

usually subclinical, may see weight loss, conjunctivitis, and lymphadenopathy

60

transmission of GPCMV

exposure to saliva carrying the virus, transplacental transmission can also occur

61

necropsy of GPCMV

karyomegaly of salivary gland epithelium

62

chronic site of replication of GPCMV

salivary glands

63

histologic description of GPCMV

eosinophilic intranuclear inclusion bodies in ductal epithelial cells

64

clinical signs of poliovirus

depression, lameness, flacid paralysis, weight loss, death

65

transmision of poliovirus

fecal oral, but not definate

66

necropsy signs of poliovirus

meningomyeloenchphalitis, perineuronal inflammation, neuronal degeneration

67

diagnosis of poliovirus

ELISA

68

Protozoa found in GP


Eimeria caviae



Klossiella cobayae



Cryptosporidium wrairi



Balantidium caviae


69

nematodes in GP

Paraspidodera uncinata

70

descriptionof Paraspidodera uncinata

cecal worm

71

most common helminth in GP

Paraspidodera uncinata

72

Mites found on GP


Chirodiscoides caviae,



Demodex caviae,



Mycoptes musculinis,



Trixacarus caviae,



Sarcoptes scabiei,



Notoderes muris


73

pathogenic mites in GP


Chirodiscoides caviae



Trixacarus caviae


74

Where is Trixacarus found?

burrowing mite, in the skin

75

Where do lesions occur with Trixacarus


trunk, inner thigs, neck, and shoulders, intense pruritis and alopecia


76

Where is Chirodiscoides found?

on hair shaft

77

Where do lesions of Chirodiscoides form?


posterior trunk, causes severe pruritis


78

lice found on GP


Gliricola porcelli



Gyropus ovalis



Trimenopan hispidum



Trimenopan jenningsi


79

most common louse found in GP


Gliricola porcelli- chewing louse


80

location to find lice in GP

ears and nape of neck

81

fleas found in GP


Ctenocephalides felis



Nosopsyllus fasciatus



Ctenocephalides porcellus


82

Cause of dermatophytosis in GP

Trichophyton mentagrophytes

83

spread of Encephalitozoon cuniculi to GP

urine of infected rabbits

84

clinical signs of Encephalitozoon cuniculi in GP

subclinical infection but may see microscopic lesions in brain and kidney (necrotic foci, microgranulomas, perivascular lymphoplasmacytic cuffs)

85

clinical signs of marginal vitamin C deficiency

conjunctivitis or upper respiratory disease

86

hypovitaminosis C, clinical signs

hemorrhage in the subperiosteum, skeletal muscles, joints (stifle, costrocondral junctions) and intestine

87

reason why GP are susceptible to Vit C deficiency

lack genetic code to produce L-gulonolactone oxidase

88

histologic changes seen in hypovitaminosis C

epiphyseal growth centers are deranged with reduced osteoid formation, deranged chondrocytes, decreased bony trabeculae in marrow cavity

89

two forms of toxemia of pregnancy


1) preeclampsia/circulatory form



2) pregnancy ketosis(fasting form)


90

timeframe of pregnancy for preeclampsia to occur?

last 2 weeks

91

pathogenesis of preeclampsia

size of uterus interupts blood flow

92

pathogenesis of fasting ketosis

size of uterus prevents proper intake of food leading to mobilization of muscle and ketones to liver for energy

93

necropsy of preeclampsia

ecchymotic hemorrhage and focal necrosis

94

necropsy of fasting ketosis

fatty infiltration of liver, kidney, adrenal glands, vessel walls

95

minerals involved in urolithiasis

Calcium, phosphourus, magnesium

96

urolithiasis is most common in what sex?

Females

97

clinical signsof hypovitaminosis A

keratitis, squamous metaplasia, crusty eyelids

98

cause of hypervitaminosis A

giving multivitamin supplement instead of just vit c

99

clinical signs of hypervitaminosis A

degeneration of cartilaginous epiphyseal plates, abnormal bone repair, teratogenic effects

100

are guinea pigs susceptible to Rickets?

dont see in GP

101

location of metastatic calcification?

skeletal and cardiac muscle fibers

102

diabetes mellitus is found in what inbred strains

Abyssinian Hartley colonies

103

GP response to Freund's complete adjuvant

pulmonary granulomas

104

frequently bred sows often show

hair thinning

105

cause of ulcerative pododermatitis or bumblefoot

Staph aureus, enters through abrasions/injury to feet, most often from wire floors

106

antibiotics associated with typhlocolitis

aminopenicillins, cephalosporins, clindamycin, streptomycin, lincomycin

107

organism associated with antibiotic associated typhlocolitis

Clostridium difficile

108

pathogenesis of antibiotic associated typhlocolitis

1) antibiodic induced suppression of resident microflora

109

fffmost common neoplasia in GP


lymphosarcoma


110

gastric ulcers can occur secondary to

uremia, ketosis, excessive stress, Citrobacter infection

111

cause of Rhabdomyomatosis

congenital abnormality of glycogen metabolism

112

causes of nephrosclerosis

autoimmune, infectious, vascular disorders, high protein diet

113

anatomical part of the ovary that is responsible for cyst formation

rete ovarii

114

description of retina of GP

paurangiotic (few vessels near optic disk)

115

amyloidosis can be seen secondary to what clinical conditions

staphylococcal pododermatitis and osteoarthritis

116

what is unique about the GP cardiovascular system?


good collateral circulation, difficult to cause infarcts


117

what is unique about the dentition of GP


they are the only rodent to have premolars



 



all teeth are open rooted and grow continuisly


118

what is the shock organ of the GP


lung


119

4 things to know about Yersinia pseudotuberculosis


1. zoonotic



2. 4 clinical states, acute disease, chronic disease, nonfatal lymphanepitis, or subclinical carrier state



3. antibiotic tx leads to carrier state



4. culture at cold temps 20-30C


120

things to know about antibiotic induced enterotoxemia- hemorrhagic typhilitis


Clostridium difficile is causative agent



caused by antibiotics or dietary change



 


121

things to know about Clostridium piliforme- Tyzzers disease


wide host range



rare in GP



triad of lesions, heart-liver-GI


122

causative agents of mastitis in GP


pasturella



klebsiella



strep



staph



coliforms


123

clinical condition caused by Cryptosporidium wrairi


greasy coat


124

kidney protozoa of GP


Klossiella cobayae



asymptomatic infecteion, incidental on necropsy


125

what antibiotics are safe for GP


fluoroquinolones



gentamicin



TMS



chloramphenicol