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Flashcards in Leukemia Deck (15):
1

Who is leukemia most common in?

Children and young adults

2

What is leukemia classified as?

Acute and chronic lymphocytic leukemia or acute and chronic myelogenous leukemia

3

In acute forms of leukemia what cells tend to be affected?

Immature blast cells

4

In chronic leukemia which cells are often affected?

Mature cells

5

Is acute leukemia often aggressive or not as aggressive?

Aggressive

6

Is chronic leukemia aggressive or not as aggressive?

Not as aggressive

7

What cells are affected in myelogenous leukemia?

Monocytes and granulocytes

8

What is the etiology of leukemia?

It is due to mutated genes, but exact cause is idiopathic

9

What are risk factors for leukemia?

Genetic predisposition, excessive radiation from X-rays, t-cell leukemia virus, and immunodeficiency

10

Is non-malignant blood cel production affected in leukemia? If so, why?

Yes. Because there is decreased space in the bond marrow and malignant cells are taking up all of the resources.

11

In leukemia, what occurs as a result of improper blood cell production in the bone marrow?

An impaired immune response and a decreased oxygen supply to the tissues because of less red blood cells being produced

12

What are manifestations of leukemia?

Anemia
Thrombocytopenia
Leukopenia
Bleeding gums
Fever
Generalized pain
Fatigue, weakness, bruising
Recurrent infection

13

What is the treatment for leukemia?

Radiation & chemo
Blood transfusions
Antimicrobials
CS factors (enhance proliferation of colony cells)
Marrow transplant

14

What is meant by induction, intensification and maintenance when speaking of treatment for leukemia? And how long does this happen for?

Inducing remission, intensifying the remission and maintaining the remission. This lasts for 12-24 months

15

Where are malignant cells found in leukaemia?

Present in circulation and may infiltrate tissues