Flashcards in Myasthena Gravis Deck (10):
What does myasthenia gravis affect
Communication between the motor neuron and the inner cared muscle cells
What is the etiology of myasthenia gravis?
Autoimmunity with an unknown trigger
Possible sensitized T cells
What is the patho of myasthenia gravis?
Autoimmunity abs target acetylcholine receptors and bind to them -> less acetylcholine is binding -> muscle weakness and weakened contractions due to less acetylcholine actions
Many people with myasthenia gravis also have an abnormal what?
Thymus due to hyperplasia or tumor (large thymus)
How is myasthenia gravis diagnosed?
Assay for ach receptor antibodies
How is myasthenia gravis treated?
Reversible anticholinesterase drugs
What is the myasthenic crisis?
Sudden worsening of symptoms and weakness severe enough to compromise ventilation
When does the myasthenic crisis usually occur?
During a period of stress
What are mnft of myasthenia gravis ?
Eye muscle weakness
Difficulty speaking (dysarthria)
Weakness in arms hands legs fingers and neck