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Flashcards in Parkinson's Disease Deck (7):
1

What is the etiology of Parkinson's

Idiopathic

2

What does Parkinson's eventually lead to?

Disability

3

What is the patho of Parkinson's?

Destruction of pigmented neuronal cells in the substantia nigra in the basal ganglia -> decreased dopamine levels -> degeneration of the dopaminergic pathway -> imbalance of excitatory (ach) and inhibitory (dopamine) neurotransmitters -> impairment of extra pyramidal reacts controlling complex body movements -> tremors, rigidity, bradykinesia, postural changes

4

How is Parkinson's diagnosed?

Hx
Presence of 2/4 Cardinal signs

5

What are mnft of Parkinson's

Tremors
Rigidity
Bradykinesia
Postural inability

6

How is Parkinson's treated?

symptom management
No actual treatment however there are medications that help the manifest ions
Levodopa
Antivirals
Dopamine agonists
Mao inhibitors (inhibit breakdown of dopamine)

7

What is Parkinson's?

A slowly professing neurological movement disorder