Flashcards in Parkinson's Disease Deck (7):
What is the etiology of Parkinson's
What does Parkinson's eventually lead to?
What is the patho of Parkinson's?
Destruction of pigmented neuronal cells in the substantia nigra in the basal ganglia -> decreased dopamine levels -> degeneration of the dopaminergic pathway -> imbalance of excitatory (ach) and inhibitory (dopamine) neurotransmitters -> impairment of extra pyramidal reacts controlling complex body movements -> tremors, rigidity, bradykinesia, postural changes
How is Parkinson's diagnosed?
Presence of 2/4 Cardinal signs
What are mnft of Parkinson's
How is Parkinson's treated?
No actual treatment however there are medications that help the manifest ions
Mao inhibitors (inhibit breakdown of dopamine)