Pathoma: Pulmonary HTN Flashcards Preview

CVPR Pulmonary (Exam 3) > Pathoma: Pulmonary HTN > Flashcards

Flashcards in Pathoma: Pulmonary HTN Deck (15):
1

Who classically gets 1a pulm HTN?

young adult females

2

What is the normal pulmonary circuit pressure?

10mmHg

2

How does pulm HTN present?

  • exertional dyspnea
  • RH failure

3

What can cause increased volume in the pulmonary circuit?

congenital heart disease (Eisenmenger's Syndrome)

4

Thickening of the vascular smooth muscle cells of the lungs leads to _____.

pulm HTN

5

What causes 2a pulm HTN?

  1. hypoxemia
  2. increased pulm circuit volume
  3. recurrent PE

5

What can PE cause?

  1. nothing- asymptomatic
  2. pulm infarction
  3. sudden death (saddle emboli)
  4. reorganization --> pulm HTN

7

Pulmonary HTN is defined as pressure higher than ____.

25mmHg

8

Pulm HTN leads to _____ and _____.

RV hypertrophy; cor pulmonale

9

This is a group of capillaries swirled together- a complication of long standing pulm HTN.

a plexiform lesion

10

What is cor pulmonale?

RH failure

11

What causes 1a pulm HTN?

unknown etiology, but familial forms due to mutation in BMPR2

12

What is a plexiform lesion?

a group of capillaries swirled together- a complication of long standing pulm HTN

14

What are the characteristics of pulmonary HTN?

  • atherosclerosis of the pulm trunk
  • smooth muscle hypertrophy of pulm a.'s
  • intimal fibrosis
  • plexiform lesions

15

What does a BMPR2 mutation cause?

1a pulm HTN via vascular smooth muscle proliferation