Alpha-2 antagonists, such as yohimbine, increase available norepinephrine and can precipitate_____, as do lactate infusions and breathing C02.
panic attacks
_____ and _____ can lead to chronically elevated levels of cortisol and norepinephrine.
Depression; anxiety disorders
What are the symptoms of panic disorder?
- shortness of breath
- sweating
- numbness and tingling around the mouth and fingers
- feelings of choking
- feelings of unreality, confusion
- feel as if they are dying of a heart attack or are going crazy
How can an anxiety attack be clinically induced?
IV infusion of sodium lactate or breathing CO2
Patients with ______ experience shortness of breath, palpitations, chest pain, fears of dying and going crazy.
panic disorder
What are the 2 anxiety components?
cognitive and the physiologic state of hyperarousal
What is the generic name for Paxil?
paroxetine
The familial risk for panic disorder suggests 40%heritability and onset is ______.
during young adulthood
Intense fear of scrutiny in public = ?
Social Phobia
OCD is a brain disease in which ______ dysregulation appears to play a significant role, particularly in the striatum, part of the basal ganglia, which includes the caudate and lentiform nucleus.
serotonin
Recurrent & unexpected attacks = ?
Panic Disorder
The familial risk for panic disorder suggests ____%heritability and onset is during young adulthood.
40
OCD is a brain disease in which serotonin dysregulation appears to play a significant role, particularly in the ____ and the ___, which includes the ____ and ____.
striatum, basal ganglia; caudate and lentiform nucleus.
What is the brand name for venlafaxine?
Effexor
What is the generic name for Lexapro?
escitalopram
Approximately 90 percent of patients with generalized anxiety disorder answer affirmatively when asked, "____?"
During the past four weeks, have you been bothered by feeling worried, tense, or anxious most of the time?
What are the first line treatments for anxiety (and major depressive) disorders?
SSRIs and venlafaxine
This is a learned meditation technique that teaches people to focus on the present moment & to accept their thoughts in a nonjudgmental manner.
mindfulness meditation
What is the brand name for escitalopram?
Lexapro
Recurrent obsessions and compulsions = ?
Obsessive-Compulsive Disorder
Obsessive-Compulsive Disorder = ?
Recurrent obsessions and compulsions
Alpha-2 antagonists, such as _____, increase available norepinephrine and can precipitate panic attacks, as do lactate infusions and breathing C02.
yohimbine
Patients with panic disorder experience ____, ____, ____, ____, and _____.
shortness of breath, palpitations, chest pain, fears of dying, and going crazy
Depression and anxiety disorders can lead to chronically elevated levels of ____ and ______.
cortisol; norepinephrine
______, such as yohimbine, increase available norepinephrine and can precipitate panic attacks, as do lactate infusions and breathing C02.
Alpha-2 antagonists
Social Phobia = ?
Intense fear of scrutiny in public
What is the brand name for paroxetine?
Paxil
Anxiety in men and women influences the onset of cardiac disease via _____, _____, and _____.
stress induced atherosclerosis, endothelial dysfunction, and reduced heart-rate variability
What is the generic name for venlafaxine?
Effexor
What is the brand name for sertraline?
Zoloft
Generalized Anxiety Disorder = ?
Intense worry about most things in life
Approximately ____ percent of patients with generalized anxiety disorder answer affirmatively when asked, "During the past four weeks, have you been bothered by feeling worried, tense, or anxious most of the time?"
90
Intense worry about most things in life = ?
Generalized Anxiety Disorder
What is mindfulness meditation?
a learned meditation technique that teaches people to focus on the present moment & to accept their thoughts in a nonjudgmental manner
Depression and anxiety disorders can cause what comorbidities?
- adverse heart rhythms
- increased blood pressure
- altered blood clotting
- elevated insulin and cholesterol levels
- Dx?
- shortness of breath
- sweating
- numbness and tingling around the mouth and fingers
- feelings of choking
- feelings of unreality, confusion
- feel as if they are dying of a heart attack or are going crazy
panic disorder
An important risk factor for developing panic disorder is ______.
childhood asthma
What is anxiety?
the response to real or imagined danger
Antidepressants should be started at ______ dose to minimize side effects in these hyper-alert and worried people.
one half (or less) of the usual starting dose
What is the generic name for Zoloft?
sertraline
Antidepressants should be started at one half (or less) of the usual starting dose to ______ in these hyper-alert and worried people.
minimize side effects
Panic Disorder = ?
Recurrent & unexpected attacks
_____ is a brain disease in which serotonin dysregulation appears to play a significant role, particularly in the striatum, part of the basal ganglia, which includes the caudate and lentiform nucleus.
OCD