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Flashcards in Unit 11 Deck (45):
1

lung ca

rt death by disease, mostly avoidable

2

mortality of lung ca

30%

3

characteristics of lung c

aggressive, invasive, metastic

4

where does lung c met to

brain, bones ,liver

5

4 primary types of lung ca

adenocarcinoma
squamous cell carcinoma
large cell carcinoma
small cell carcinoma

6

2 cats of primary lung ca

1 - not small cell lung ca
2 - small cell lung ca

7

what ca's are in nsclc

adenocaracino
squamous cell carcinoma
large cell carcinoma

8

what cas are in sclc

small cell carcinoma

9

what is the 5th type of primary lung ca

mixed group

10

what percent of lug ca is adenocarcinoma

30

11

what percent of lung ca is squamous cell carcinoma

30

12

what percent of lung ca is large cell carcinoma

12

13

what percent of lung ca is small cell carcinoma

22

14

et of lung ca

smoking (80)
toxins (eg asbestos)
genetic predisposition

15

where does 95% of lung ca originate

bronchi

16

where does squamous cell carcinoma originate

hilum of central bronchi

17

where does squamous cell carcinoma spread

regionally to hilar nodes

18

who has increased dispostion to squamous cell carcinoma

men

19

what may tumor spread of squamous cell carcinoma cause

impact to pericardium -> dec heart fx

20

where does adenocarcinoma originate

peripherary

21

what is adenocarcinoma assoc with

alveoli and bronchioles

22

who has an increase in adenocarcinoma

women, non smokers

23

where does large cell carcinoma originate

peripheray

24

characteristics of large cell carcinoma

large, undifferentiated cells
mets early

25

which ca out of all nsclc has poorest prognisis

large cell carcinoma

26

characteristic of cells in small cell carcinoma

small, oval, oat like cells

27

which population experiences an increase in small cell carcinoma

99% smokers

28

characteristics of small cell carcinoma

aggressive, invasive with slim prognosis

29

where does small cell carcinoma met to early

brain

30

what percent of small cell carcinoma has mets at dx

70

31

what does small cell carcinoma do to local tissue

invades quickly

32

what is said about excision of small cell carcinoma

hard to excise, not resectable, cells may not be massed together

33

what tx does small cell carincoma have inc response to

radiation, said to be radiosensitive

34

what is a commone SE of small cell carcinoma

paraneoplastic syndrome

35

what conditions are included in paraneoplastic syndrome

SIADH (adh)
cushings (cortisol, adrenocortico)

36

what are mnfts of all lung ca's based on

type, site, ext of local invasion, mets

37

central mnfts of lung ca

large aw obst, impaired breathing, unexplained coughing, wheezing, dyspnea

38

other mnfts of lung ca

paraneoplastic syndrome
hemoptysis
pain
cardiac mnfts

39

hemoptysis

coughing blood rt vessel damage caused by malignancy

40

cardiac mnfts in lung ca

rt inc P on heart. tumor has to affect pericardium, central malignancy only

41

dx for lung ca

hx, px
rule out URT, CLD
cxr, CT, US, MRI
bronchophy/needle biopsy
sputum analysis/ bronchiol wash

42

what is tx for lung ca basedo n

type

43

tx for nsclc

sx, radiation, chemo

44

tx for sclc

chemo radiation

45

why does lung ca have poor prognosis

no good screen -> dec detection