Flashcards in Unit 3 Part 3 Deck (28):
1
acute pancreatitis
inflm of pancreas
2
what happens in acute pancreatitis
autodigestion
3
what is autodigestion
not IR related
sec of enzymes by pancreas that attack it
4
what tissue produces most of the ezs in in pancreatic auto digestion
exocrine
5
what is said about the prognosis of pancreatitis
self limiting but life threatening
6
Et of pancreatitis (6)
alcohol abuse (70%)
gallstones
hyperlipidemia
idipathic
inflm
other : eg pancreatic trauma, drugs
7
why does alcohol cause pancreatitis
alcohol stimulates pancreatic juice sec -> excessive sec -> bile enters other ducts -> ez are activated outside duodenum prematurel -> ez attack pancreas
8
why do gallstones cause pancreatitis
block ducts -> inc sec moving down ducts -> ez activiated -> ez attack pancras
9
why does hyperlipidemia lt pancreatitis
extra fat -> extra bile -> stones -> duct blockage
10
why are ez actiavted prematurely in pancreas
inc bile sec while there is a block results in bile flowing through other ducts until it reaches the pancreas, activating ez prematurely
11
how do ez cause pancreatic damage
auto digestion
hemmor
necrosis
12
when does the hepatopancreatic sphincter open
when bile and pancreatic juice are released
13
what does alcohol do to the hepatopancreatic sphincter
constricts it
14
what happens when the hepatopancreatic sphincter is constricted
mixing of ducts
15
what is important to remember about the pancreas' sensitivity and fx reserve
highly sensitive
dec fx reserve
16
when does pancreatitis onset
following heavy meal/alcohol binge (with hx of alcoholism) dt inc stomach content -> inc sec
17
what type of pain is felt in pancreatitis
sev abdm pain
epigastric pain that radiates to back
18
why does 3rd spacing occur in pancreatitis
rt vital organ + extensive inflm, triggering inflm response -> vasodilation and fluid shift out of pancreas into 3rd space
19
why does vascular collapse of the pancreas occur
dt l/o patency rt dec volume in vasculature
20
is there risk for hypovolima in pancreatitis
yes
21
what ez are elevated in blood during pancreatitis
amylase
lipase
22
which ez is pancreatitc specific
lipase
23
tx of pancreatitis (7)
pain mgmt
NPO
ICU
sx
tx complications
vol expansion and paracenthesis
no alcohol
24
how do we manage pain in pancreatitis
IV opioids
25
why is the pancreatic pt NPO
to stop sec of juice /ez by pan
26
why are DM patients especially NPO
correct metb abn which could result in DM dt inability to rls I when pt ingests food
27
when is the pancreatitis pt in the ICU
severe cases resulting in renal, CV, and hepatobiliary problems
28