Unit 3 Part 3 Flashcards Preview

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Flashcards in Unit 3 Part 3 Deck (28):
1

acute pancreatitis

inflm of pancreas

2

what happens in acute pancreatitis

autodigestion

3

what is autodigestion

not IR related
sec of enzymes by pancreas that attack it

4

what tissue produces most of the ezs in in pancreatic auto digestion

exocrine

5

what is said about the prognosis of pancreatitis

self limiting but life threatening

6

Et of pancreatitis (6)

alcohol abuse (70%)
gallstones
hyperlipidemia
idipathic
inflm
other : eg pancreatic trauma, drugs

7

why does alcohol cause pancreatitis

alcohol stimulates pancreatic juice sec -> excessive sec -> bile enters other ducts -> ez are activated outside duodenum prematurel -> ez attack pancreas

8

why do gallstones cause pancreatitis

block ducts -> inc sec moving down ducts -> ez activiated -> ez attack pancras

9

why does hyperlipidemia lt pancreatitis

extra fat -> extra bile -> stones -> duct blockage

10

why are ez actiavted prematurely in pancreas

inc bile sec while there is a block results in bile flowing through other ducts until it reaches the pancreas, activating ez prematurely

11

how do ez cause pancreatic damage

auto digestion
hemmor
necrosis

12

when does the hepatopancreatic sphincter open

when bile and pancreatic juice are released

13

what does alcohol do to the hepatopancreatic sphincter

constricts it

14

what happens when the hepatopancreatic sphincter is constricted

mixing of ducts

15

what is important to remember about the pancreas' sensitivity and fx reserve

highly sensitive
dec fx reserve

16

when does pancreatitis onset

following heavy meal/alcohol binge (with hx of alcoholism) dt inc stomach content -> inc sec

17

what type of pain is felt in pancreatitis

sev abdm pain
epigastric pain that radiates to back

18

why does 3rd spacing occur in pancreatitis

rt vital organ + extensive inflm, triggering inflm response -> vasodilation and fluid shift out of pancreas into 3rd space

19

why does vascular collapse of the pancreas occur

dt l/o patency rt dec volume in vasculature

20

is there risk for hypovolima in pancreatitis

yes

21

what ez are elevated in blood during pancreatitis

amylase
lipase

22

which ez is pancreatitc specific

lipase

23

tx of pancreatitis (7)

pain mgmt
NPO
ICU
sx
tx complications
vol expansion and paracenthesis
no alcohol

24

how do we manage pain in pancreatitis

IV opioids

25

why is the pancreatic pt NPO

to stop sec of juice /ez by pan

26

why are DM patients especially NPO

correct metb abn which could result in DM dt inability to rls I when pt ingests food

27

when is the pancreatitis pt in the ICU

severe cases resulting in renal, CV, and hepatobiliary problems

28

sx as atx

to remove stones