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Flashcards in Unit 5 Deck (55):
1

cleft lift

incomplete fusion of maxillary/nasal strs

2

when in gestation does cleft lip occur

wk 5-8

3

et of cleft lip

congenital dt teratogen

4

how is cleft lip described

indent, fissure, uni or bilateral

5

incidence of cleft lip

1-700 life births

6

what teratogens may cause cleft lip

smoking
viral infc
folic acid def

7

cleft palate

incomplete fusion of palatine str

8

when in gestation does cleft palate occur

wk 9-12

9

what str is malformed in cleft palate

nasal str

10

occurance of cleft palate

1-2000

11

predispostions for cleft palate

smoking

12

tx for cleft palate

sx or graft

13

major issues with cleft palate

speech
breathing

14

pyloric stenosis

muslce hypertrophy and constriction at pyloric sphincter

15

what is obstructed with the constriction of the pyloric sphincter

entrance to duodenum

16

incidence of pyloric stenosis

1 in 1000 births

17

when does pyloric stenosis occur

2-8 weeks old NOT CONGENITAL

18

whats the ratio of males to females with pyloric stenosis

4:1

19

et of pyloric stenosis

idipathic

20

what 3 conditions are linked to pyloric stenosis

hypergastrinemia
PGE (prostaglandin E)
erythromycin exposure

21

which babies have inc incidence of PGE

babies with HF

22

patho of pyloric stenosis

hypertrophy -> constr -> inflm -> obstr

23

mnfts of pyloric stenosis

projectile vomitting
dehydration
malnourishment

24

dx of pyloric stenosis

Hx, Px
US
URQ palpation

25

what will an US in a babe with pyloric stenosis show

pyloric reigon enlargement

26

tx for pyloric stenosis

sx to remove excess m

27

when is there in a inc in gastroesophageal reflux

first 3m of life

28

et of gastroesophageal reflux

neuromuscular issue dt functional sphincter problem

29

what is happening with the distal esophageal sphincter in gastroesophageal reflux

incompetent and allows reflux

30

what sphincter is affected in gastroesophageal reflux

distal esophageal sphincter

31

how does esophagitis occur in gastroesophageal reflux

gi content enters esphogous causing inflm

32

what is the course of gastroesophageal reflux

self limiting within a year

33

tx for GE reflux

symptomatic tx
H2Ra, PPI
modify teaching
sev case: fundoplication

34

what teaching is modified for teaching about GE reflux

small meals
thicken feed
positioning

35

which babies have inc incidence of Hirschsprung disease

inc in male babies

36

incidence of hirschspruing disese HD

1 in 5000 births

37

et of HD

congenital/genetic

38

what gene mutates in HD

Ret proto onco gene (RET)

39

what chr is the RET gene on

10

40

what happens if RET gene is absent

problems signalling between cells, absence of PNS tissue, ganglia in colon

41

what happens in HD

absence of PNS tissue in ganglia resulting in localized area of colon with dec peristalsis

42

where is there abdm distention in HD

area BEFORE the spot in the colon with no PNS

43

tx of HD

sx to remove aganglionic segment of PNS

44

intussception

part of intestine invaginates into another part

45

where does intussception normally occur

at iliocelcal clave

46

why does intussception occur at the iliocecal valve

the smaller ilium is able to move into the larger cecum

47

incidence of intussception

1-4 in 1000

48

what does invagination lead to

obstr of lumen

49

what happens when the lumen is obstr

inflm -> edema into lumen

50

what happens when there is inc edema in lumen in intussception

inc intraluminal P -> ischemia -> necrosis, perf, peritonitis

51

why does ischemia occur when there is inc intraluminal P

the intraluminal P is > then the venous P causing stasis, no arterial blood moving in, necrosis

52

tx of intussusception

hydrostatic reduction

53

hydrostatic reduction

use of water soluble contrast medium and air P to gently dec intussusception with an endoscope

54

when DONT you use sx in intussusception

obstr/perf

55

when cant you use hydrostatic reduction for intussusception

if perforation is suspected