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Flashcards in Uterine Deck (43)
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1

What are the Oxytocics

Stimulants
Oxytocin
Ergonovine
Methylergonovine
Carboprost tromethamine
Dinoprostone
Misoprostol

2

What are the Tocolytics

Relaxants
Mg sulfate
Indomethacin
Nifedipine
Atosiban
Terbutaline (beta 2 agonists)

3

How does Oxytocin work

Activate Gq - SM contraction
Increase PG synthesis

4

When is the uterus more sensitive to Oxytocin

2nd half of pregnancy

5

DOC for induction of labor

Oxytocin

6

When do you give oxytocin

Augment dysfunctional labor
Limit post-partum hemorrhage (1st line)
Induce abortion

7

What is the Oxytocin challenge test

Measure HR to check for fetal hypoxia

8

What are the AE for Oxytocin

Fetal distress
Placental abruption
Uterine rupture
Activate vasopressin receptors

9

What are partial alpha agonists and have some 5HT activity

Ergonovine
Methylergonovine

10

Sensitivity to what increases in pregnancy

Ergot alkaloids

11

2nd line for post-partum hemorrhage

Ergonovine
Methylergonovine

12

What is found in breast milk

Ergonovine
Methylergonovine

13

What can cause gangrene in nursing infant

Ergonovine
Methylergonovine

14

Contraindication for Ergot Alkaloids

Angina
MI
Pregnancy
CVA
HTN

15

Which is a PGF2 alpha analog

Carboprost tromethamine

16

Give if pt has benign hydatiform mole

Dinoprostone

17

Used to induce abortion in 2nd trimester

Carboprost tromethamine
Dinoprostone

18

3rd line for post-partum hemorrhage

Carboprost tromethamine

19

Used to evacuate uterus after missed abortion

Dinoprostone

20

Used to ripen the cervix

Dinoprostone
Misoprostone

21

Which is a PGE1 analog

Misoprostol

22

What is the only FDA approved use of Misoprostol

NSAID induced gastric ulcers

23

What else can Misoprostol be used for

Induce labor
Post-partum hemorrhage

24

What is the leading cause of neonatal mortality

Preterm birth (< 37wks)

25

What is the most popular tocolytic

Mg sulfate

26

Which tocolytic has similar efficacy to terbutaline but with better tolerance

Mg sulfate

27

Which tocolytics cross the placenta

Mg sulfate
Indomethacin

28

How does Mg sulfate work

Uncouples excitation-contraction in myometrium

29

Mg sulfate AE

Resp depression
Cardiac arrest

30

How does Indomethacin act

Inhibit PG synthesis (NSAID)