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Flashcards in Diuretics Deck (54)
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1

What are the loop diuretics

Furosemide
Toresemide

2

What are the thiazides

Chlorthalidone
Hydrochlorothiazide
Metolazone

3

What are the K sparing diuretics

Spironolactone
Eplerenone
Amiloride
Triamterene

4

What is the CAH inhibitor

Acetazolamide

5

What is the osmotic diuretic

Mannitol

6

What is the ADH antagonist and acts on V1 and 2

Conivaptan

7

What do loop diuretics act on

NKCC2

8

What do thiazides act on

NCCT

9

What acts as an aldosterone antagonist

Spironolactone
Eplerenone

10

What acts on ENaC

Amiloride
Triamterene

11

DOC for acute pulm edema with HF

Loop diuretics

12

HTN in DI

Thiazides

13

Main AE for Loop

Ototoxicity
Hypokalemia

14

Main AE for aldosterone agonists

Irregular menstrual cycle
gynecomastia
Impotence

15

Main AE for Acetazolamide

Metabolic acidosis

16

Main AE for Mannitol

Dehydration

17

What are the most effective diuretic

Loop

18

Which diuretic class decrease PVR and BP even after volume recovery

Thiazides

19

What are the sulfa derivatives

Thiazides

20

What is the NKCC2

Na/Cl/K cotransporter

21

Where do loops act

LOH duh

22

What increases PG synthesis via COX 2

Loop diuretics

23

Under what conditions can you give loop diuretic

Hypercalcemia
Hyperkalemia

24

What is the urine composition in a pt on loop diuretics

Increased Ca, Na, K, Mg, volume

25

What is the urine composition in a pt on thiazides

Increased Na, K, Cl, Mg, volume
Decreased Ca

26

AE of Loops

Hyperuricemia (since renal clearance is affected)
Acute hypovolemia
Hypomagnesemia
Allergies (sulfa)

27

What is NCCT

NA/Cl cotransporter

28

Where is NCCT

DCT

29

Do thiazides have a ceiling effect

Yes

30

When can you give a thiazide

HTN
Mild HF
Hypercalcemia